7DN4
The crystal structure of Cpd8 in complex with BPTF bromodomain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Nucleosome-remodeling factor subunit BPTF | polymer | 123 | 14455.4 | 6 | UniProt (Q12830) Pfam (PF00439) In PDB | Homo sapiens (Human) | Bromodomain and PHD finger-containing transcription factor,Fetal Alz-50 clone 1 protein,Fetal Alzheimer antigen |
| 2 | A, B, C, D, E... | 3-methyl-2-[[(3R,5R)-1-methyl-5-phenyl-piperidin-3-yl]amino]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-one | non-polymer | 338.4 | 6 | Chemie (JC3) |
Sequence modifications
A, B, C, D, E, F: 2791 - 2911 (UniProt: Q12830)
| PDB | External Database | Details |
|---|---|---|
| Ser 2789 | - | expression tag |
| Met 2790 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 86732.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2030.7 | |
| All* | Total formula weight | 88763.2 |
