7DIY

Crystal structure of SARS-CoV-2 nsp10 bound to nsp14-exoribonuclease domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	nsp10 protein	polymer	144	15214.4	1	UniProt (P0DTD1) Pfam (PF09401)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	pp1ab,ORF1ab polyprotein
2	B (B)	nsp14-ExoN protein	polymer	294	32992.0	1	UniProt (P0DTD1) Pfam (PF06471)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	pp1ab,ORF1ab polyprotein
3	C, D, E, F (A, B)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
4	G (B)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	H, I (A, B)	water	water		18.0	29	Chemie (HOH)

Sequence modifications

A: 1 - 139 (UniProt: P0DTD1)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

B: 1 - 289 (UniProt: P0DTD1)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Ala -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	48206.4
Non-Polymers*	Number of molecules	5
	Total formula weight	285.9
All*	Total formula weight	48492.3

*Water molecules are not included.