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7DIY

Crystal structure of SARS-CoV-2 nsp10 bound to nsp14-exoribonuclease domain

Functional Information from GO Data
ChainGOidnamespacecontents
A0003723molecular_functionRNA binding
A0008270molecular_functionzinc ion binding
A0019079biological_processviral genome replication
B0000175molecular_function3'-5'-RNA exonuclease activity
B0004532molecular_functionRNA exonuclease activity
B0008168molecular_functionmethyltransferase activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues5
DetailsACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01298
ChainResidueDetails
BASP90
BGLU92
BGLU191
BHIS268
BASP273
ACYS120
ACYS128
ACYS130

site_idSWS_FT_FI2
Number of Residues13
DetailsBINDING: BINDING => ECO:0000269|PubMed:36546776
ChainResidueDetails
BASP90
BHIS264
BHIS268
BASP273
BCYS279
BGLU92
BGLU191
BCYS207
BCYS210
BCYS226
BHIS229
BHIS257
BCYS261

226707

PDB entries from 2024-10-30

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