7DF1

Crystal structure of human CD98 heavy chain extracellular domain in complex with S1-F4 scFv

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	4F2 cell-surface antigen heavy chain	polymer	420	46244.0	4	UniProt (P08195) Pfam (PF00128) In PDB	Homo sapiens (Human)	4F2hc,4F2 heavy chain antigen,Lymphocyte activation antigen 4F2 large subunit,Solute carrier family 3 member 2
2	H, E, F, G	S1-F4 VH	polymer	140	14741.4	4		Homo sapiens
3	L, I, J, K	IGL c2062_light_IGKV4-1_IGKJ5	polymer	122	13581.0	4	UniProt (A0A5C2G3X0) Pfam (PF07686) In PDB	Homo sapiens (Human)	IGL c2147_light_IGKV4-1_IGKJ5

Sequence modifications

A, B, C, D: 111 - 529 (UniProt: P08195)

PDB	External Database	Details
Ser 110	-	expression tag

L, I, J, K: 1 - 107 (UniProt: A0A5C2G3X0)

PDB	External Database	Details
Asn 93	Ser 99	conflict
Ala 108	-	expression tag
Ala 109	-	expression tag
Ala 110	-	expression tag
His 111	-	expression tag
His 112	-	expression tag
His 113	-	expression tag
His 114	-	expression tag
His 115	-	expression tag
His 116	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	298265.3
All*	Total formula weight	298265.3

*Water molecules are not included.