7D5O
C-Src in complex with TAS-120
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Proto-oncogene tyrosine-protein kinase Src | polymer | 286 | 32726.6 | 2 | UniProt (P00523) Pfam (PF07714) | Gallus gallus (chicken) | Proto-oncogene c-Src,pp60c-src,p60-Src |
| 2 | C, D (B, A) | 1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one | non-polymer | 418.4 | 2 | Chemie (TZ0) | |||
| 3 | E, F (B, A) | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence modifications
B, A: 251 - 533 (UniProt: P00523)
| PDB | External Database | Details |
|---|---|---|
| Gly 248 | - | expression tag |
| His 249 | - | expression tag |
| Met 250 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65453.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 836.9 | |
| All* | Total formula weight | 66290.2 |
