7D44

eIF2B-eIF2(aP), aP2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Translation initiation factor eIF-2B subunit alpha	polymer	305	33754.1	2	UniProt (Q14232) Pfam (PF01008) In PDB	Homo sapiens (Human)	eIF2Balpha,eIF-2B GDP-GTP exchange factor subunit alpha
2	C, D	Translation initiation factor eIF-2B subunit beta	polymer	351	39039.5	2	UniProt (P49770) Pfam (PF01008) In PDB	Homo sapiens (Human)	eIF2Bbeta,S20I15,S20III15,eIF-2B GDP-GTP exchange factor subunit beta
3	E, F	Translation initiation factor eIF-2B subunit gamma	polymer	452	50304.2	2	UniProt (Q9NR50) Pfam (PF00483) In PDB	Homo sapiens (Human)	eIF2Bgamma,eIF2Bg,eIF-2B GDP-GTP exchange factor subunit gamma
4	G, H	Translation initiation factor eIF-2B subunit delta	polymer	523	57640.2	2	UniProt (Q9UI10) Pfam (PF01008) In PDB	Homo sapiens (Human)	eIF2Bdelta,eIF-2B GDP-GTP exchange factor subunit delta
5	I, J	Translation initiation factor eIF-2B subunit epsilon	polymer	721	80466.6	2	UniProt (Q13144) Pfam (PF02020) In PDB	Homo sapiens (Human)	eIF2Bepsilon,eIF-2B GDP-GTP exchange factor subunit epsilon
6	K, L	Eukaryotic translation initiation factor 2 subunit 1	polymer	315	36241.2	2	UniProt (P05198) Pfam (PF00575) Pfam (PF07541) In PDB	Homo sapiens (Human)	P-eIF2alpha,Eukaryotic translation initiation factor 2 subunit alpha,eIF-2alpha

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	594891.7
All*	Total formula weight	594891.7

*Water molecules are not included.