7CXR

Cryo-EM structure of human TMEM120A/TACAN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	MCherry fluorescent protein,Ion channel TACAN	polymer	625	72643.6	2	UniProt (X5DSL3) UniProt (Q9BXJ8) Pfam (PF01353) Pfam (PF07851) In PDB	Anaplasma marginale	Transmembrane protein 120A,Transmembrane protein induced by tumor necrosis factor alpha,TMEM120A/TACAN

Sequence modifications

A, B: -245 - -10 (UniProt: X5DSL3)

PDB	External Database	Details
Met -281	-	expression tag
Asp -280	-	expression tag
Tyr -279	-	expression tag
Lys -278	-	expression tag
Asp -277	-	expression tag
Asp -276	-	expression tag
Asp -275	-	expression tag
Asp -274	-	expression tag
Lys -273	-	expression tag
Gly -272	-	expression tag
Ser -271	-	expression tag
Asp -270	-	expression tag
Tyr -269	-	expression tag
Lys -268	-	expression tag
Asp -267	-	expression tag
Asp -266	-	expression tag
Asp -265	-	expression tag
Asp -264	-	expression tag
Lys -263	-	expression tag
Gly -262	-	expression tag
Ser -261	-	expression tag
Asp -260	-	expression tag
Tyr -259	-	expression tag
Lys -258	-	expression tag
Asp -257	-	expression tag
Asp -256	-	expression tag
Asp -255	-	expression tag
Asp -254	-	expression tag
Lys -253	-	expression tag
Gly -252	-	expression tag
Ser -251	-	expression tag
Asp -250	-	expression tag
Glu -249	-	expression tag
Val -248	-	expression tag
Asp -247	-	expression tag
Ala -246	-	expression tag
Leu -9	-	linker
Glu -8	-	linker
Val -7	-	linker
Leu -6	-	linker
Phe -5	-	linker
Gln -4	-	linker
Gly -3	-	linker
Pro -2	-	linker
Glu -1	-	linker
Phe 0	-	linker

A, B: 1 - 343 (UniProt: Q9BXJ8)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	145287.1
All*	Total formula weight	145287.1

*Water molecules are not included.