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7CMZ

Crystal Structure of BRCT7/8 in Complex with the APS Motif of PHF8

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA topoisomerase 2-binding protein 1polymer23026059.81UniProt (Q92547)
Pfam (PF00533)
Homo sapiens (Human)DNA topoisomerase II-beta-binding protein 1,TopBP1,DNA topoisomerase II-binding protein 1
2B
(B)
Histone lysine demethylase PHF8polymer222422.51UniProt (Q9UPP1)Homo sapiensPHD finger protein 8,[histone H3]-dimethyl-L-lysine(36) demethylase PHF8,[histone H3]-dimethyl-L-lysine(9) demethylase PHF8
3C
(A)
POTASSIUM IONnon-polymer39.11Chemie (K)
4D
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
5E, F
(A, B)
waterwater18.0289Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28482.3
Non-Polymers*Number of molecules2
Total formula weight62.1
All*Total formula weight28544.4
*Water molecules are not included.

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PDB entries from 2024-11-06

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