7CMS
Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with chuangxinmycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tryptophan--tRNA ligase | polymer | 328 | 37225.7 | 2 | UniProt (P00953) Pfam (PF00579) | Geobacillus stearothermophilus | Tryptophanyl-tRNA synthetase,TrpRS |
| 2 | C, E (A, B) | (5~{S},6~{R})-5-methyl-7-thia-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,8,10-tetraene-6-carboxylic acid | non-polymer | 233.3 | 2 | Chemie (9E0) | |||
| 3 | D, F (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 468 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 328 (UniProt: P00953)
| PDB | External Database | Details |
|---|---|---|
| Leu 64 | Lys 64 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74451.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 656.5 | |
| All* | Total formula weight | 75107.9 |
