7CMM
Crystal structure of TEAD1-YBD in complex with K-975
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Transcriptional enhancer factor TEF-1 | polymer | 230 | 26570.2 | 4 | UniProt (P28347) Pfam (PF17725) | Homo sapiens (Human) | NTEF-1,Protein GT-IIC,TEA domain family member 1,TEAD-1,Transcription factor 13,TCF-13 |
| 2 | E, F, G, H (A, B, C, D) | N-[3-(4-chloranylphenoxy)-4-methyl-phenyl]propanamide | non-polymer | 289.8 | 4 | Chemie (KK9) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 207 - 426 (UniProt: P28347)
| PDB | External Database | Details |
|---|---|---|
| Gly 197 | - | expression tag |
| Pro 198 | - | expression tag |
| Leu 199 | - | expression tag |
| Gly 200 | - | expression tag |
| Ser 201 | - | expression tag |
| Glu 202 | - | expression tag |
| Asn 203 | - | expression tag |
| Leu 204 | - | expression tag |
| Tyr 205 | - | expression tag |
| Phe 206 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 106280.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1159.0 | |
| All* | Total formula weight | 107439.7 |
