7CM0
Crystal structure of a glutaminyl cyclase in complex with NHV-1009
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutaminyl-peptide cyclotransferase | polymer | 327 | 37399.2 | 4 | UniProt (Q16769) Pfam (PF04389) | Homo sapiens (Human) | Glutaminyl cyclase,sQC,Glutaminyl-tRNA cyclotransferase,Glutamyl cyclase,EC |
| 2 | E, G, I, K (A, B, C, D) | 1-(cyclopentylmethyl)-1-[3-methoxy-4-(2-morpholin-4-ylethoxy)phenyl]-3-[3-(5-methylimidazol-1-yl)propyl]urea | non-polymer | 499.6 | 4 | Chemie (G5R) | |||
| 3 | F, H, J, L (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 149597.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2260.2 | |
| All* | Total formula weight | 151857.2 |
