7CKK
Structural complex of FTO bound with Dac51
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Alpha-ketoglutarate-dependent dioxygenase FTO | polymer | 473 | 54378.3 | 1 | UniProt (Q9C0B1) Pfam (PF12933) Pfam (PF12934) In PDB | Homo sapiens (Human) | Fat mass and obesity-associated protein,U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO,U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO,mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO,m6A(m)-demethylase FTO,mRNA N(6)-methyladenosine demethylase FTO,tRNA N1-methyl adenine demethylase FTO |
2 | A | N-OXALYLGLYCINE | non-polymer | 147.1 | 1 | Chemie (OGA) | |||
3 | A | 2-{[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino}-N-hydroxybenzamide | non-polymer | 391.3 | 1 | Chemie (B6C) | |||
4 | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A: 32 - 500 (UniProt: Q9C0B1)
PDB | External Database | Details |
---|---|---|
Gly 28 | - | expression tag |
Ser 29 | - | expression tag |
His 30 | - | expression tag |
Met 31 | - | expression tag |
Leu 45 | Lys 45 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 54378.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 538.3 | |
All* | Total formula weight | 54916.6 |