7CKK
Structural complex of FTO bound with Dac51
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-ketoglutarate-dependent dioxygenase FTO | polymer | 473 | 54378.3 | 1 | UniProt (Q9C0B1) Pfam (PF12933) Pfam (PF12934) | Homo sapiens (Human) | Fat mass and obesity-associated protein,U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO,U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO,mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO,m6A(m)-demethylase FTO,mRNA N(6)-methyladenosine demethylase FTO,tRNA N1-methyl adenine demethylase FTO |
| 2 | B (A) | N-OXALYLGLYCINE | non-polymer | 147.1 | 1 | Chemie (OGA) | |||
| 3 | C (A) | 2-{[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino}-N-hydroxybenzamide | non-polymer | 391.3 | 1 | Chemie (B6C) | |||
| 4 | D (A) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A: 32 - 500 (UniProt: Q9C0B1)
| PDB | External Database | Details |
|---|---|---|
| Gly 28 | - | expression tag |
| Ser 29 | - | expression tag |
| His 30 | - | expression tag |
| Met 31 | - | expression tag |
| Leu 45 | Lys 45 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 54378.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 538.3 | |
| All* | Total formula weight | 54916.6 |
