7CFO
Crystal structure of human RXRalpha ligand binding domain complexed with CBTF-EE.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Retinoic acid receptor RXR-alpha | polymer | 243 | 27124.3 | 4 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha |
| 2 | E, F, H (A, B, C) | 1-[3-(2-ethoxyethoxy)-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl]-2-(trifluoromethyl)benzimidazole-5-carboxylic acid | non-polymer | 504.5 | 3 | Chemie (WZ6) | |||
| 3 | G, I (B, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 224 - 462 (UniProt: P19793)
| PDB | External Database | Details |
|---|---|---|
| Gly 220 | - | expression tag |
| Ser 221 | - | expression tag |
| Ser 222 | - | expression tag |
| His 223 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 108497.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1697.8 | |
| All* | Total formula weight | 110195.0 |
