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7CDD

Crystal structure of LSD1-CoREST in complex with PRSFLVRR peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ALysine-specific histone demethylase 1Apolymer66974333.01UniProt (O60341)
Pfam (PF04433)
Pfam (PF01593)
In PDB
Homo sapiens (Human)BRAF35-HDAC complex protein BHC110,Flavin-containing amine oxidase domain-containing protein 2
2BREST corepressor 1polymer14015850.91UniProt (Q9UKL0)
Pfam (PF20878)
Pfam (PF00249)
In PDB
Homo sapiens (Human)Protein CoREST
3CPRO-ARG-SER-PHE-LEU-VAL-ARG-ARGpolymer81033.31Homo sapiens
4AFLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.51Chemie (FAD)
5AGLYCEROLnon-polymer92.12Chemie (GOL)
6waterwater18.087Chemie (HOH)
Sequence modifications
A: 172 - 833 (UniProt: O60341)
PDBExternal DatabaseDetails
Gly 165-expression tag
Pro 166-expression tag
Leu 167-expression tag
Gly 168-expression tag
Ser 169-expression tag
His 170-expression tag
Met 171-expression tag
B: 308 - 440 (UniProt: Q9UKL0)
PDBExternal DatabaseDetails
Gly 301-expression tag
Ser 302-expression tag
Ser 303-expression tag
Gly 304-expression tag
Ser 305-expression tag
Ala 306-expression tag
Ser 307-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight91217.2
Non-Polymers*Number of molecules3
Total formula weight969.7
All*Total formula weight92187.0
*Water molecules are not included.

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PDB entries from 2024-07-10

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