7CCZ

Crystal structure of the ES2 intermediate form of human hydroxymethylbilane synthase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Porphobilinogen deaminase	polymer	361	39383.0	2	UniProt (P08397) Pfam (PF01379) Pfam (PF03900)	Homo sapiens (Human)	PBG-D,Hydroxymethylbilane synthase,HMBS,Pre-uroporphyrinogen synthase
2	C, D (A, B)	3-[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-3-(3-hydroxy-3-oxopropyl)-5-methyl-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-1~{H}-pyrrol-3-yl]propanoic acid	non-polymer		838.8	2	Chemie (7J8)
3	E, F (A, B)	water	water		18.0	366	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	78766.0
Non-Polymers*	Number of molecules	2
	Total formula weight	1677.6
All*	Total formula weight	80443.6

*Water molecules are not included.