7C6B
Crystal structure of Ago2 MID domain in complex with 6-(3-(2-carboxyethyl)phenyl)purine riboside monophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Protein argonaute-2 | polymer | 139 | 15465.2 | 3 | UniProt (Q9UKV8) Pfam (PF16487) In PDB | Homo sapiens (Human) | hAgo2,Argonaute RISC catalytic component 2,Eukaryotic translation initiation factor 2C 2,eIF2C 2,PAZ Piwi domain protein,PPD,Protein slicer |
| 2 | A, B, C | 3-[3-[9-[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]purin-6-yl]phenyl]propanoic acid | non-polymer | 480.4 | 3 | Chemie (K2R) | |||
| 3 | C | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | water | water | 18.0 | 283 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 46395.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1631.0 | |
| All* | Total formula weight | 48026.6 |
