7C61
Crystal structure of 5-HT1B-BRIL and SRP2070_Fab complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | L | IGG LIGHT CHAIN | polymer | 214 | 23681.1 | 1 | Mus musculus | ||
| 2 | H | IGG HEAVY CHAIN | polymer | 323 | 35237.8 | 1 | Mus musculus | ||
| 3 | A | 5-hydroxytryptamine receptor 1B,Soluble cytochrome b562,5-hydroxytryptamine receptor 1B | polymer | 399 | 45114.5 | 1 | UniProt (P28222) UniProt (P0ABE7) Pfam (PF00001) Pfam (PF07361) In PDB | Homo sapiens (Human) | 5-HT1B,S12,Serotonin 1D beta receptor,5-HT-1D-beta,Serotonin receptor 1B,Cytochrome b-562,5-HT1B,S12,Serotonin 1D beta receptor,5-HT-1D-beta,Serotonin receptor 1B |
| 4 | A | Ergotamine | non-polymer | 581.7 | 1 | Chemie (ERM) |
Sequence modifications
A: 33 - 239 (UniProt: P28222)
A: 240 - 345 (UniProt: P0ABE7)
A: null - 430 (UniProt: P28222)
| PDB | External Database | Details |
|---|---|---|
| Gly 32 | - | expression tag |
| Trp 138 | Leu 138 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Trp 246 | Met 29 | engineered mutation |
| Ile 341 | His 124 | engineered mutation |
| Leu 345 | Arg 128 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 104033.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 581.7 | |
| All* | Total formula weight | 104615.0 |
