7C60
Crystal structure of Keap1 in complex with monoethyl fumarate (MEF)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Kelch-like ECH-associated protein 1 | polymer | 310 | 34113.1 | 1 | UniProt (Q9Z2X8) Pfam (PF01344) In PDB | Mus musculus (Mouse) | Cytosolic inhibitor of Nrf2,INrf2 |
2 | A | (~{Z})-4-ethoxy-4-oxidanylidene-but-2-enoic acid | non-polymer | 144.1 | 2 | Chemie (NF3) | |||
3 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
4 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
5 | water | water | 18.0 | 491 | Chemie (HOH) |
Sequence modifications
A: 324 - 616 (UniProt: Q9Z2X8)
PDB | External Database | Details |
---|---|---|
His 307 | - | expression tag |
His 308 | - | expression tag |
His 309 | - | expression tag |
His 310 | - | expression tag |
His 311 | - | expression tag |
His 312 | - | expression tag |
Ser 313 | - | expression tag |
Ser 314 | - | expression tag |
Gly 315 | - | expression tag |
Leu 316 | - | expression tag |
Val 317 | - | expression tag |
Pro 318 | - | expression tag |
Arg 319 | - | expression tag |
Gly 320 | - | expression tag |
Ser 321 | - | expression tag |
His 322 | - | expression tag |
Met 323 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 34113.1 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 539.4 | |
All* | Total formula weight | 34652.5 |