7C5E
Crystal structure of Keap1 in complex with fumarate (FUM)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Kelch-like ECH-associated protein 1 | polymer | 314 | 34475.5 | 1 | UniProt (Q9Z2X8) Pfam (PF01344) | Mus musculus (Mouse) | Cytosolic inhibitor of Nrf2,INrf2 |
| 2 | B, C, F (A) | FUMARIC ACID | non-polymer | 116.1 | 3 | Chemie (FUM) | |||
| 3 | D, G (A) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 4 | E (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 5 | H, I (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | J (A) | water | water | 18.0 | 353 | Chemie (HOH) |
Sequence modifications
A: 324 - 616 (UniProt: Q9Z2X8)
| PDB | External Database | Details |
|---|---|---|
| Met 303 | - | initiating methionine |
| Gly 304 | - | expression tag |
| Ser 305 | - | expression tag |
| Ser 306 | - | expression tag |
| His 307 | - | expression tag |
| His 308 | - | expression tag |
| His 309 | - | expression tag |
| His 310 | - | expression tag |
| His 311 | - | expression tag |
| His 312 | - | expression tag |
| Ser 313 | - | expression tag |
| Ser 314 | - | expression tag |
| Gly 315 | - | expression tag |
| Leu 316 | - | expression tag |
| Val 317 | - | expression tag |
| Pro 318 | - | expression tag |
| Arg 319 | - | expression tag |
| Gly 320 | - | expression tag |
| Ser 321 | - | expression tag |
| His 322 | - | expression tag |
| Met 323 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34475.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 808.6 | |
| All* | Total formula weight | 35284.1 |
