Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008134 | molecular_function | transcription factor binding |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0031463 | cellular_component | Cul3-RING ubiquitin ligase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue FUM A 801 |
| Chain | Residue |
| A | TYR334 |
| A | ACT806 |
| A | HOH913 |
| A | HOH926 |
| A | HOH940 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue FUM A 802 |
| Chain | Residue |
| A | HOH901 |
| A | HOH985 |
| A | VAL369 |
| A | VAL370 |
| A | GLY371 |
| A | GLY372 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue ACT A 803 |
| Chain | Residue |
| A | ARG354 |
| A | LEU355 |
| A | ASP357 |
| A | HIS552 |
| A | HOH903 |
| A | HOH904 |
| A | HOH1112 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue PGE A 804 |
| Chain | Residue |
| A | SER340 |
| A | ASP357 |
| A | LEU358 |
| A | GLN359 |
| A | ARG551 |
| A | HOH907 |
| A | HOH921 |
| A | HOH1036 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue FUM A 805 |
| Chain | Residue |
| A | ARG415 |
| A | ARG483 |
| A | SER508 |
| A | GLY509 |
| A | SER555 |
| A | HOH917 |
| A | HOH926 |
| A | HOH948 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 806 |
| Chain | Residue |
| A | ARG380 |
| A | ASN382 |
| A | ASN414 |
| A | ARG415 |
| A | FUM801 |
| A | HOH978 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 A 807 |
| Chain | Residue |
| A | ILE435 |
| A | HIS436 |
| A | HIS437 |
| A | SER438 |
| A | SER439 |
| A | ARG494 |
| A | HOH909 |
| A | HOH1000 |
| A | HOH1061 |
| A | HOH1065 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 808 |
| Chain | Residue |
| A | CYS434 |
| A | HIS436 |
| A | ARG459 |
| A | ARG494 |
| A | ARG498 |
| A | HOH902 |
| A | HOH931 |
| A | HOH998 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 45 |
| Details | Repeat: {"description":"Kelch 1"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 50 |
| Details | Repeat: {"description":"Kelch 2"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"Kelch 3"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"Kelch 4"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 45 |
| Details | Repeat: {"description":"Kelch 5"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"Kelch 6"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Sensor for electrophilic agents","evidences":[{"source":"PubMed","id":"20498371","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"S-(2-succinyl)cysteine","evidences":[{"source":"PubMed","id":"22014577","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"S-cGMP-cysteine","evidences":[{"source":"PubMed","id":"20498371","evidenceCode":"ECO:0000269"}]} |
