7C08
Crystal structure of S34Y mutant of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J, M... | Splicing factor U2AF 23 kDa subunit | polymer | 216 | 25142.3 | 9 | UniProt (Q09176) Pfam (PF00642) Pfam (PF00076) In PDB | Schizosaccharomyces pombe 972h- (Fission yeast) | U2 auxiliary factor 23 kDa subunit,U2AF23,U2 snRNP auxiliary factor small subunit |
| 2 | B, E, H, K, N... | Splicing factor U2AF 59 kDa subunit | polymer | 69 | 7828.9 | 9 | UniProt (P36629) In PDB | Schizosaccharomyces pombe 972h- (Fission yeast) | U2 auxiliary factor 59 kDa subunit,U2AF59,U2 snRNP auxiliary factor large subunit |
| 3 | C, F, I, L, O... | RNA (5'-R(*U*UP*AP*GP*GP*U)-3') | polymer | 6 | 1893.2 | 9 | synthetic construct | ||
| 4 | A, D, G, J, M... | ZINC ION | non-polymer | 65.4 | 18 | Chemie (ZN) |
Sequence modifications
A, D, G, J, M, P, S, V, Y: 1 - 216 (UniProt: Q09176)
| PDB | External Database | Details |
|---|---|---|
| Tyr 34 | Ser 34 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 27 |
| Total formula weight | 313779.4 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 1177.4 | |
| All* | Total formula weight | 314956.8 |
