7BV5

Crystal structure of the yeast heterodimeric ADAT2/3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	tRNA-specific adenosine deaminase subunit TAD2	polymer	253	28589.8	2	UniProt (P47058) Pfam (PF00383)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ATADT2, tRNA-specific adenosine-34 deaminase subunit TAD2
2	C, D (C, D)	tRNA-specific adenosine deaminase subunit TAD3	polymer	328	37738.0	2	UniProt (Q9URQ3) Pfam (PF00383)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ADAT3, tRNA-specific adenosine-34 deaminase subunit TAD3
3	E, F, G, H (A, B, C, D)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
4	I, J, K, L (A, B, C, D)	water	water		18.0	108	Chemie (HOH)

Sequence modifications

A, B: 2 - 250 (UniProt: P47058)

PDB	External Database	Details
Met -2	-	expression tag
Ala -1	-	expression tag
Asp 0	-	expression tag
Leu 1	-	expression tag

C, D: 1 - 322 (UniProt: Q9URQ3)

PDB	External Database	Details
Gly -5	-	expression tag
Pro -4	-	expression tag
His -3	-	expression tag
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	132655.6
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	132917.2

*Water molecules are not included.