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7BJ1

Crystal structure of SMYD3 with diperodon S enantiomer bound to allosteric site

Replaces:  6Z2R
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AHistone-lysine N-methyltransferase SMYD3polymer43149460.41UniProt (Q9H7B4)
Pfam (PF00856)
Pfam (PF01753)
In PDB
Homo sapiens (Human)SET and MYND domain-containing protein 3,Zinc finger MYND domain-containing protein 1
2AS-ADENOSYLMETHIONINEnon-polymer398.41Chemie (SAM)
3ADiperodon (S-enantiomer)non-polymer397.51Chemie (QKT)
4AZINC IONnon-polymer65.43Chemie (ZN)
5AACETATE IONnon-polymer59.02Chemie (ACT)
6AGLYCEROLnon-polymer92.12Chemie (GOL)
7waterwater18.0523Chemie (HOH)
Sequence modifications
A: 1 - 428 (UniProt: Q9H7B4)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
Asn 13Lys 13engineered mutation
Arg 140Lys 140engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight49460.4
Non-Polymers*Number of molecules9
Total formula weight1294.4
All*Total formula weight50754.8
*Water molecules are not included.

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PDB entries from 2024-05-15

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