7BIX

Crystal structure of UMPK from M. tuberculosis in complex with UDP and UTP (C2 form)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Uridylate kinase	polymer	281	29625.9	12	UniProt (P9WHK5) Pfam (PF00696) In PDB	Mycobacterium tuberculosis H37Rv	UK,Uridine monophosphate kinase,UMPK
2	A, C, D, G, I...	URIDINE 5'-TRIPHOSPHATE	non-polymer		484.1	6	Chemie (UTP)
3	B, C, D, E, H...	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	8	Chemie (UDP)
4		water	water		18.0	55	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 1 - 261 (UniProt: P9WHK5)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	355510.7
Non-Polymers*	Number of molecules	14
	Total formula weight	6138.1
All*	Total formula weight	361648.9

*Water molecules are not included.