7BI2
PI3KC2aDeltaN and DeltaC-C2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha,Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | polymer | 1157 | 131361.9 | 1 | UniProt (Q61194) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) Pfam (PF00787) | Mus musculus (House Mouse) | PtdIns-3-kinase C2 subunit alpha,Cpk-m,Phosphoinositide 3-kinase-C2-alpha,p170,PtdIns-3-kinase C2 subunit alpha,Cpk-m,Phosphoinositide 3-kinase-C2-alpha,p170 |
| 2 | B (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 3 | C (A) | 9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2(1H)-one | non-polymer | 432.4 | 1 | Chemie (17G) | |||
| 4 | D, E, F, G, H (A) | IODIDE ION | non-polymer | 126.9 | 5 | Chemie (IOD) | |||
| 5 | I (A) | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A: 3 - 158 (UniProt: Q61194)
A: 163 - 1157 (UniProt: Q61194)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ala 2 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 159 | - | linker |
| Ser 160 | - | linker |
| Gly 161 | - | linker |
| Ser 162 | - | linker |
| Gly 286 | Ala 668 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 131361.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1129.0 | |
| All* | Total formula weight | 132490.9 |
