7BBG
CRYSTAL STRUCTURE OF HLA-A2-WT1-RMF AND FAB 11D06
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MHC class I antigen | polymer | 309 | 35401.9 | 1 | UniProt (Q861F7) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (A0A140T913) | Homo sapiens (Human) | |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C (C) | Wilms tumor 1 (WT1) derived peptide | polymer | 9 | 1109.3 | 1 | UniProt (by SIFTS) (P19544) | Homo sapiens | |
| 4 | D (H) | Heavy chain of Fab fragment 11D06 | polymer | 223 | 23528.4 | 1 | Homo sapiens (Human) | ||
| 5 | E (L) | Light chain of Fab fragment 11D06 | polymer | 213 | 23331.8 | 1 | Homo sapiens (Human) | ||
| 6 | F, G, H, I, J (A, H) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 7 | K, L, M, N, O (A, B, C, H, L) | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
A: 1 - 275 (UniProt: Q861F7)
B: 2 - 100 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Gly 276 | - | expression tag |
| Gly 277 | - | expression tag |
| Gly 278 | - | expression tag |
| Gly 279 | - | expression tag |
| Ser 280 | - | expression tag |
| Gly 281 | - | expression tag |
| Gly 282 | - | expression tag |
| Gly 283 | - | expression tag |
| Gly 284 | - | expression tag |
| Ser 285 | - | expression tag |
| Gly 286 | - | expression tag |
| Ser 287 | - | expression tag |
| Gly 288 | - | expression tag |
| Leu 289 | - | expression tag |
| Asn 290 | - | expression tag |
| Asp 291 | - | expression tag |
| Ile 292 | - | expression tag |
| Phe 293 | - | expression tag |
| Glu 294 | - | expression tag |
| Ala 295 | - | expression tag |
| Gln 296 | - | expression tag |
| Lys 297 | - | expression tag |
| Ile 298 | - | expression tag |
| Glu 299 | - | expression tag |
| Trp 300 | - | expression tag |
| His 301 | - | expression tag |
| Glu 302 | - | expression tag |
| His 303 | - | expression tag |
| His 304 | - | expression tag |
| His 305 | - | expression tag |
| His 306 | - | expression tag |
| His 307 | - | expression tag |
| His 308 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 95250.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 114.9 | |
| All* | Total formula weight | 95365.7 |
