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7B05

TRPC4 in complex with inhibitor GFB-8749

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DTransient receptor potential cation channel subfamily c member 4apolymer915105204.64UniProt (U3N7D8)
Pfam (PF12796)
Pfam (PF00023)
Pfam (PF08344)
Pfam (PF00520)
In PDB
Danio rerio (Zebrafish)
2A, B, C, D4-[4-[[4,4-bis(fluoranyl)cyclohexyl]methyl]-3-oxidanylidene-piperazin-1-yl]-5-chloranyl-1~{H}-pyridazin-6-onenon-polymer360.84Chemie (SJQ)
3A, B, C, DCALCIUM IONnon-polymer40.14Chemie (CA)
4A, B, C, D(2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoatenon-polymer368.44Chemie (44E)
Sequence modifications
A, B, C, D: 2 - 915 (UniProt: U3N7D8)
PDBExternal DatabaseDetails
Gly 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight420818.6
Non-Polymers*Number of molecules12
Total formula weight3076.9
All*Total formula weight423895.5
*Water molecules are not included.

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PDB entries from 2024-07-17

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