7AVL
Crystal structure of SOS1 in complex with compound 4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Son of sevenless homolog 1 | polymer | 487 | 57103.3 | 2 | UniProt (Q07889) Pfam (PF00618) Pfam (PF00617) In PDB | Homo sapiens (Human) | SOS-1 |
2 | A, B | IMIDAZOLE | non-polymer | 69.1 | 7 | Chemie (IMD) | |||
3 | A, B | 6,7-dimethoxy-2-methyl-~{N}-[(1~{R})-1-phenylethyl]quinazolin-4-amine | non-polymer | 323.4 | 2 | Chemie (S2Z) | |||
4 | water | water | 18.0 | 933 | Chemie (HOH) |
Sequence modifications
A, B: 564 - 1049 (UniProt: Q07889)
PDB | External Database | Details |
---|---|---|
Gly 563 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 114206.6 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1130.4 | |
All* | Total formula weight | 115336.9 |