7ASS
OXA-48_L67F_CAZ. What Doesnt Kill You Makes You Stronger: Sub-MIC Selection Drives Cryptic Evolution of OXA-48
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Beta-lactamase | polymer | 265 | 30473.7 | 4 | UniProt (Q6XEC0) Pfam (PF00905) | Klebsiella pneumoniae | |
| 2 | E, G, H, I, K (B, C, D) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 3 | F, J (C, D) | hydrolyzed ceftazidime | non-polymer | 565.6 | 2 | Chemie (RYE) | |||
| 4 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 797 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 265 (UniProt: Q6XEC0)
| PDB | External Database | Details |
|---|---|---|
| Phe 67 | Leu 67 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 121895.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1308.5 | |
| All* | Total formula weight | 123203.4 |
