7AE9
Crystal structure of mono-AMPylated HEPN(R46E) toxin in complex with MNT antitoxin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | HEPN toxin | polymer | 157 | 18312.6 | 4 | UniProt (A0A0B0QJR1) Pfam (PF01934) In PDB | Aphanizomenon flos-aquae 2012/KM1/D3 | |
2 | E, F, G, H | MNT ANTITOXIN | polymer | 150 | 17380.0 | 4 | UniProt (A0A0B0QJN8) Pfam (PF18765) In PDB | Aphanizomenon flos-aquae 2012/KM1/D3 | |
3 | A, B, D | 2',3'-DIDEOXYADENOSINE-5'-MONOPHOSPHATE | non-polymer | 315.2 | 3 | Chemie (2DA) | |||
4 | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 5 - 147 (UniProt: A0A0B0QJR1)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Thr 2 | - | expression tag |
Asn 3 | - | expression tag |
Ile 4 | - | expression tag |
Glu 46 | Arg 43 | engineered mutation |
Leu 148 | - | expression tag |
Glu 149 | - | expression tag |
Ser 150 | - | expression tag |
Gly 151 | - | expression tag |
His 152 | - | expression tag |
His 153 | - | expression tag |
His 154 | - | expression tag |
His 155 | - | expression tag |
His 156 | - | expression tag |
His 157 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 142770.7 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 945.7 | |
All* | Total formula weight | 143716.4 |