7A59
Crimean-Congo Hemorrhagic Fever Virus Envelope Glycoprotein Gc W1191H/W1197A/W1199A Mutant in Postfusion Conformation (Orthorhombic Crystal Form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Envelopment polyprotein | polymer | 538 | 59870.8 | 3 | UniProt (Q8JSZ3) Pfam (PF01561) Pfam (PF20682) | Crimean-Congo hemorrhagic fever virus strain IbAr10200 (CCHFV) | M polyprotein |
| 2 | D (D) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G00395TQ) | |||
| 3 | E, J (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 4 | F, G, H, K, L... (A, B, C) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 5 | I (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | N, O, P (A, B, C) | water | water | 18.0 | 729 | Chemie (HOH) |
Sequence modifications
A, B, C: 1041 - 1561 (UniProt: Q8JSZ3)
| PDB | External Database | Details |
|---|---|---|
| His 1191 | Trp 1191 | engineered mutation |
| Ala 1197 | Trp 1197 | engineered mutation |
| Ala 1199 | Trp 1199 | engineered mutation |
| Glu 1562 | - | expression tag |
| Asn 1563 | - | expression tag |
| Leu 1564 | - | expression tag |
| Tyr 1565 | - | expression tag |
| Phe 1566 | - | expression tag |
| Gln 1567 | - | expression tag |
| Ser 1568 | - | expression tag |
| Ala 1569 | - | expression tag |
| Gly 1570 | - | expression tag |
| Trp 1571 | - | expression tag |
| Ser 1572 | - | expression tag |
| His 1573 | - | expression tag |
| Pro 1574 | - | expression tag |
| Gln 1575 | - | expression tag |
| Phe 1576 | - | expression tag |
| Glu 1577 | - | expression tag |
| Lys 1578 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 179612.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 894.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 750.1 | |
| All* | Total formula weight | 181257.3 |
