7A3O
Crystal structure of dengue 1 virus envelope glycoprotein in complex with the scFv fragment of the broadly neutralizing human antibody EDE1 C10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Core protein | polymer | 432 | 47077.3 | 1 | UniProt (Q9II02) Pfam (PF00869) Pfam (PF02832) | Dengue virus 1 | Envelope protein E,Flavivirin protease NS2B regulatory subunit,Flavivirin protease NS3 catalytic subunit,Genome polyprotein,Matrix protein,Non-structural protein 1,Non-structural protein 2A,Non-structural protein 2B,Non-structural protein 3,Non-structural protein 4A,Non-structural protein 4B,Peptide 2k,Peptide pr,Protein prM,RNA-directed RNA polymerase NS5,Serine protease NS3,Serine protease subunit NS2B,Small envelope protein M |
| 2 | B (H) | Single chain variable fragment (scFv) from antibody EDE1 C10 | polymer | 144 | 15679.2 | 1 | Homo sapiens (Human) | ||
| 3 | C (L) | Single chain variable fragment (scFv) from antibody EDE1 C10 | polymer | 154 | 15632.8 | 1 | Homo sapiens (Human) | ||
| 4 | D (B) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 5 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | F, G, H, I, J... (A, L) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 7 | L, M (A, H) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 1 - 395 (UniProt: Q9II02)
| PDB | External Database | Details |
|---|---|---|
| Ala 396 | - | expression tag |
| Ala 397 | - | expression tag |
| Asp 398 | - | expression tag |
| Asp 399 | - | expression tag |
| Asp 400 | - | expression tag |
| Asp 401 | - | expression tag |
| Lys 402 | - | expression tag |
| Ala 403 | - | expression tag |
| Gly 404 | - | expression tag |
| Trp 405 | - | expression tag |
| Ser 406 | - | expression tag |
| His 407 | - | expression tag |
| Pro 408 | - | expression tag |
| Gln 409 | - | expression tag |
| Phe 410 | - | expression tag |
| Glu 411 | - | expression tag |
| Lys 412 | - | expression tag |
| Gly 413 | - | expression tag |
| Gly 414 | - | expression tag |
| Gly 415 | - | expression tag |
| Ser 416 | - | expression tag |
| Gly 417 | - | expression tag |
| Gly 418 | - | expression tag |
| Gly 419 | - | expression tag |
| Ser 420 | - | expression tag |
| Gly 421 | - | expression tag |
| Gly 422 | - | expression tag |
| Gly 423 | - | expression tag |
| Ser 424 | - | expression tag |
| Trp 425 | - | expression tag |
| Ser 426 | - | expression tag |
| His 427 | - | expression tag |
| Pro 428 | - | expression tag |
| Gln 429 | - | expression tag |
| Phe 430 | - | expression tag |
| Glu 431 | - | expression tag |
| Lys 432 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 78389.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 367.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 668.5 | |
| All* | Total formula weight | 79425.1 |
