7A3N
Crystal structure of Zika virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE1 C10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Core protein | polymer | 414 | 45138.2 | 1 | UniProt (A0A1U9YHM2) Pfam (PF00869) Pfam (PF02832) UniProt (by SIFTS) (A0A024B7W1) In PDB | Zika virus (ZIKV) | Envelope protein E,Flavivirin protease NS2B regulatory subunit,Flavivirin protease NS3 catalytic subunit,Genome polyprotein,Matrix protein,Non-structural protein 1,Non-structural protein 2A,Non-structural protein 2B,Non-structural protein 3,Non-structural protein 4A,Non-structural protein 4B,Peptide 2k,Peptide pr,Protein prM,RNA-directed RNA polymerase NS5,Serine protease NS3,Serine protease subunit NS2B,Small envelope protein M |
| 2 | H | EDE1 C10 Fab | polymer | 268 | 28989.0 | 1 | Homo sapiens (Human) | ||
| 3 | L | EDE1 C10 Fab | polymer | 217 | 22800.1 | 1 | Homo sapiens (Human) | ||
| 4 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | water | water | 18.0 | 312 | Chemie (HOH) |
Sequence modifications
A: 1 - 409 (UniProt: A0A1U9YHM2)
| PDB | External Database | Details |
|---|---|---|
| Gly 410 | - | expression tag |
| Leu 411 | - | expression tag |
| Val 412 | - | expression tag |
| Pro 413 | - | expression tag |
| Arg 414 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 96927.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 96967.4 |
