7A0D
The Crystal Structure of Bovine Thrombin in complex with Hirudin (C16U/C28U) at 1.6 Angstroms Resolution
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (HHH) | Prothrombin | polymer | 259 | 29772.4 | 1 | UniProt (P00735) Pfam (PF00089) | Bos taurus (Bovine) | Coagulation factor II |
| 2 | B (III) | Hirudin variant-1 | polymer | 65 | 7067.3 | 1 | UniProt (P01050) Pfam (PF00713) | Hirudo medicinalis | Hirudin-1,Hirudin-I |
| 3 | C (LLL) | Prothrombin | polymer | 49 | 5735.2 | 1 | UniProt (P00735) Pfam (PF09396) | Bos taurus (Bovine) | Coagulation factor II |
| 4 | D (HaH) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E (HHH) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | F, G, H (HHH, III, LLL) | water | water | 18.0 | 357 | Chemie (HOH) |
Sequence modifications
III: 1 - 65 (UniProt: P01050)
| PDB | External Database | Details |
|---|---|---|
| Sec 16 | Cys 16 | modified residue |
| Sec 28 | Cys 28 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 42575.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 23.0 | |
| All* | Total formula weight | 43022.3 |
