6ZZ4

Crystal structure of the PTPN2 C216G mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Tyrosine-protein phosphatase non-receptor type 2	polymer	314	36612.5	2	UniProt (P17706) Pfam (PF00102)	Homo sapiens (Human)	T-cell protein-tyrosine phosphatase,TCPTP
2	C, D, E, F, G... (A, B)	PHOSPHATE ION	non-polymer		95.0	6	Chemie (PO4)
3	I, J (A, B)	water	water		18.0	173	Chemie (HOH)

Sequence modifications

A, B: 1 - 314 (UniProt: P17706)

PDB	External Database	Details
Gly 216	Cys 216	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73225.0
Non-Polymers*	Number of molecules	6
	Total formula weight	569.8
All*	Total formula weight	73794.8

*Water molecules are not included.