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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6ZLW

SARS-CoV-2 Nsp1 bound to the human 40S ribosomal subunit

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1B40S ribosomal protein SApolymer29532883.91UniProt (P08865)
Pfam (PF00318)
Pfam (PF16122)
In PDB		Homo sapiens (Human)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Colon carcinoma laminin-binding protein,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,Small ribosomal subunit protein uS2
2C40S ribosomal protein S3apolymer26430002.11UniProt (P61247)
Pfam (PF01015)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1
3D40S ribosomal protein S2polymer29331376.51UniProt (P15880)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Homo sapiens (Human)40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5
4E40S ribosomal protein S4, X isoformpolymer26329654.91UniProt (P62701)
Pfam (PF16121)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
In PDB		Homo sapiens (Human)SCR10,Single copy abundant mRNA protein,Small ribosomal subunit protein eS4
5F40S ribosomal protein S3polymer24326729.41UniProt (P23396)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS3
6G40S ribosomal protein S6polymer24928751.91UniProt (P62753)
Pfam (PF01092)
In PDB		Homo sapiens (Human)Phosphoprotein NP33,Small ribosomal subunit protein eS6
7H40S ribosomal protein S7polymer19422168.91UniProt (P62081)
Pfam (PF01251)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS7
8I40S ribosomal protein S8polymer20824263.41UniProt (P62241)
Pfam (PF01201)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS8
9J40S ribosomal protein S9polymer19422641.61UniProt (P46781)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS4
10K40S ribosomal protein S5polymer20422913.51UniProt (P46782)
Pfam (PF00177)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS7
11L40S ribosomal protein S11polymer15818468.81UniProt (P62280)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS17
12M40S ribosomal protein S10polymer16518933.81UniProt (P46783)
Pfam (PF03501)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS10
13N40S ribosomal protein S13polymer15117259.41UniProt (P62277)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS15
14O40S ribosomal protein S12polymer13214539.01UniProt (P25398)
Pfam (PF01248)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS12
15P40S ribosomal protein S14polymer15116302.81UniProt (P62263)
Pfam (PF00411)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS11
16Q40S ribosomal protein S15polymer14517076.21UniProt (P62841)
Pfam (PF00203)
In PDB		Homo sapiens (Human)RIG protein,Small ribosomal subunit protein uS19
17R40S ribosomal protein S16polymer14616477.41UniProt (P62249)
Pfam (PF00380)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS9
18S40S ribosomal protein S17polymer13515578.21UniProt (P08708)
Pfam (PF00833)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS17
19T40S ribosomal protein S18polymer15217759.81UniProt (P62269)
Pfam (PF00416)
In PDB		Homo sapiens (Human)Ke-3,Ke3,Small ribosomal subunit protein uS13
20U40S ribosomal protein S19polymer14516091.61UniProt (P39019)
Pfam (PF01090)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS19
21V40S ribosomal protein S20polymer11913398.81UniProt (P60866)
Pfam (PF00338)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS10
22W40S ribosomal protein S15apolymer13014865.61UniProt (P62244)
Pfam (PF00410)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS8
23X40S ribosomal protein S23polymer14315844.71UniProt (P62266)
Pfam (PF00164)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS12
24Y40S ribosomal protein S24polymer13315463.31UniProt (P62847)
Pfam (PF01282)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS24
25Z40S ribosomal protein S21polymer839124.41UniProt (P63220)
Pfam (PF01249)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS21
26a40S ribosomal protein S25polymer12513776.21UniProt (P62851)
Pfam (PF03297)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS25
27b40S ribosomal protein S27polymer849480.21UniProt (P42677)
Pfam (PF01667)
In PDB		Homo sapiens (Human)Metallopan-stimulin 1,MPS-1,Small ribosomal subunit protein eS27
28c40S ribosomal protein S26polymer11513047.51UniProt (P62854)
Pfam (PF01283)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS26
29d40S ribosomal protein S28polymer697855.11UniProt (P62857)
Pfam (PF01200)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS28
30e40S ribosomal protein S30polymer596668.91UniProt (P62861)
Pfam (PF04758)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS30
31f40S ribosomal protein S29polymer566690.81UniProt (P62273)
Pfam (PF00253)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS14
32gUbiquitin-40S ribosomal protein S27apolymer15618004.01UniProt (P62979)
Pfam (PF00240)
Pfam (PF01599)
In PDB		Homo sapiens (Human)Ubiquitin carboxyl extension protein 80
33h60S ribosomal protein L41polymer253473.51UniProt (P62945)
Pfam (PF05162)
In PDB		Homo sapiens (Human)HG12,Large ribosomal subunit protein eL41
34jReceptor of activated protein C kinase 1polymer31735115.71UniProt (P63244)
Pfam (PF00400)
In PDB		Homo sapiens (Human)Cell proliferation-inducing gene 21 protein,Guanine nucleotide-binding protein subunit beta-2-like 1,Guanine nucleotide-binding protein subunit beta-like protein 12.3,Human lung cancer oncogene 7 protein,HLC-7,Receptor for activated C kinase,Small ribosomal subunit protein RACK1
35218S ribosomal RNApolymer1868602432.61GenBank (337376)Homo sapiens (Human)
36iNon-structural protein 1polymer18019801.31UniProt (P0DTD1)
Pfam (PF11501)
In PDB		Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)pp1ab,ORF1ab polyprotein,Non-structural protein 1
37c, f, gZINC IONnon-polymer65.43Chemie (ZN)
Sequence modifications
2: 1 - 1869 (GenBank: 337376)
PDBExternal DatabaseDetails
C 1772G 1872conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains36
Total formula weight1244915.4
Non-Polymers*Number of molecules3
Total formula weight196.2
All*Total formula weight1245111.6
*Water molecules are not included.

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PDB entries from 2024-04-17

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