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6ZLW

SARS-CoV-2 Nsp1 bound to the human 40S ribosomal subunit

Functional Information from GO Data
ChainGOidnamespacecontents
B0000028biological_processribosomal small subunit assembly
B0001618molecular_functionvirus receptor activity
B0002181biological_processcytoplasmic translation
B0003723molecular_functionRNA binding
B0003735molecular_functionstructural constituent of ribosome
B0005055molecular_functionlaminin receptor activity
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005840cellular_componentribosome
B0005886cellular_componentplasma membrane
B0006412biological_processtranslation
B0007155biological_processcell adhesion
B0015935cellular_componentsmall ribosomal subunit
B0016020cellular_componentmembrane
B0022626cellular_componentcytosolic ribosome
B0022627cellular_componentcytosolic small ribosomal subunit
B0030686cellular_component90S preribosome
B0043022molecular_functionribosome binding
B0043236molecular_functionlaminin binding
B0046718biological_processsymbiont entry into host cell
B0070062cellular_componentextracellular exosome
B1990904cellular_componentribonucleoprotein complex
C0002181biological_processcytoplasmic translation
C0003723molecular_functionRNA binding
C0003735molecular_functionstructural constituent of ribosome
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005730cellular_componentnucleolus
C0005737cellular_componentcytoplasm
C0005783cellular_componentendoplasmic reticulum
C0005829cellular_componentcytosol
C0005840cellular_componentribosome
C0005925cellular_componentfocal adhesion
C0006412biological_processtranslation
C0006413biological_processtranslational initiation
C0022626cellular_componentcytosolic ribosome
C0022627cellular_componentcytosolic small ribosomal subunit
C0030154biological_processcell differentiation
C0032040cellular_componentsmall-subunit processome
C0042274biological_processribosomal small subunit biogenesis
C0043066biological_processnegative regulation of apoptotic process
C0045202cellular_componentsynapse
C0048027molecular_functionmRNA 5'-UTR binding
C0070062cellular_componentextracellular exosome
C1990904cellular_componentribonucleoprotein complex
D0002181biological_processcytoplasmic translation
D0003723molecular_functionRNA binding
D0003729molecular_functionmRNA binding
D0003735molecular_functionstructural constituent of ribosome
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005730cellular_componentnucleolus
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0005840cellular_componentribosome
D0005925cellular_componentfocal adhesion
D0006412biological_processtranslation
D0015935cellular_componentsmall ribosomal subunit
D0016020cellular_componentmembrane
D0017134molecular_functionfibroblast growth factor binding
D0019899molecular_functionenzyme binding
D0022626cellular_componentcytosolic ribosome
D0022627cellular_componentcytosolic small ribosomal subunit
D0045296molecular_functioncadherin binding
D0051443biological_processpositive regulation of ubiquitin-protein transferase activity
D0070062cellular_componentextracellular exosome
D1990904cellular_componentribonucleoprotein complex
E0002181biological_processcytoplasmic translation
E0003723molecular_functionRNA binding
E0003735molecular_functionstructural constituent of ribosome
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005654cellular_componentnucleoplasm
E0005730cellular_componentnucleolus
E0005737cellular_componentcytoplasm
E0005829cellular_componentcytosol
E0005840cellular_componentribosome
E0005925cellular_componentfocal adhesion
E0006412biological_processtranslation
E0008284biological_processpositive regulation of cell population proliferation
E0015935cellular_componentsmall ribosomal subunit
E0016020cellular_componentmembrane
E0019843molecular_functionrRNA binding
E0022626cellular_componentcytosolic ribosome
E0022627cellular_componentcytosolic small ribosomal subunit
E0032040cellular_componentsmall-subunit processome
E0036464cellular_componentcytoplasmic ribonucleoprotein granule
E0042274biological_processribosomal small subunit biogenesis
E0045202cellular_componentsynapse
E0045727biological_processpositive regulation of translation
E0070062cellular_componentextracellular exosome
E1990904cellular_componentribonucleoprotein complex
F0000977molecular_functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
F0002181biological_processcytoplasmic translation
F0003677molecular_functionDNA binding
F0003684molecular_functiondamaged DNA binding
F0003723molecular_functionRNA binding
F0003729molecular_functionmRNA binding
F0003735molecular_functionstructural constituent of ribosome
F0003906molecular_functionDNA-(apurinic or apyrimidinic site) endonuclease activity
F0004520molecular_functionDNA endonuclease activity
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005654cellular_componentnucleoplasm
F0005730cellular_componentnucleolus
F0005737cellular_componentcytoplasm
F0005739cellular_componentmitochondrion
F0005743cellular_componentmitochondrial inner membrane
F0005759cellular_componentmitochondrial matrix
F0005783cellular_componentendoplasmic reticulum
F0005819cellular_componentspindle
F0005829cellular_componentcytosol
F0005840cellular_componentribosome
F0005856cellular_componentcytoskeleton
F0005886cellular_componentplasma membrane
F0005925cellular_componentfocal adhesion
F0006281biological_processDNA repair
F0006284biological_processbase-excision repair
F0006412biological_processtranslation
F0006413biological_processtranslational initiation
F0006417biological_processregulation of translation
F0006915biological_processapoptotic process
F0006974biological_processDNA damage response
F0007049biological_processcell cycle
F0007059biological_processchromosome segregation
F0008017molecular_functionmicrotubule binding
F0010628biological_processpositive regulation of gene expression
F0014069cellular_componentpostsynaptic density
F0015631molecular_functiontubulin binding
F0015935cellular_componentsmall ribosomal subunit
F0016020cellular_componentmembrane
F0016829molecular_functionlyase activity
F0017148biological_processnegative regulation of translation
F0019104molecular_functionDNA N-glycosylase activity
F0019899molecular_functionenzyme binding
F0019900molecular_functionkinase binding
F0019901molecular_functionprotein kinase binding
F0022626cellular_componentcytosolic ribosome
F0022627cellular_componentcytosolic small ribosomal subunit
F0030544molecular_functionHsp70 protein binding
F0031116biological_processpositive regulation of microtubule polymerization
F0031334biological_processpositive regulation of protein-containing complex assembly
F0031397biological_processnegative regulation of protein ubiquitination
F0032079biological_processpositive regulation of endodeoxyribonuclease activity
F0032357molecular_functionoxidized purine DNA binding
F0032358molecular_functionoxidized pyrimidine DNA binding
F0032587cellular_componentruffle membrane
F0032743biological_processpositive regulation of interleukin-2 production
F0034614biological_processcellular response to reactive oxygen species
F0042104biological_processpositive regulation of activated T cell proliferation
F0042981biological_processregulation of apoptotic process
F0043507biological_processpositive regulation of JUN kinase activity
F0044390molecular_functionubiquitin-like protein conjugating enzyme binding
F0044877molecular_functionprotein-containing complex binding
F0045202cellular_componentsynapse
F0045738biological_processnegative regulation of DNA repair
F0045739biological_processpositive regulation of DNA repair
F0050862biological_processpositive regulation of T cell receptor signaling pathway
F0051018molecular_functionprotein kinase A binding
F0051092biological_processpositive regulation of NF-kappaB transcription factor activity
F0051225biological_processspindle assembly
F0051301biological_processcell division
F0051536molecular_functioniron-sulfur cluster binding
F0051879molecular_functionHsp90 protein binding
F0061481biological_processresponse to TNF agonist
F0070062cellular_componentextracellular exosome
F0070181molecular_functionsmall ribosomal subunit rRNA binding
F0070301biological_processcellular response to hydrogen peroxide
F0071159cellular_componentNF-kappaB complex
F0071356biological_processcellular response to tumor necrosis factor
F0072686cellular_componentmitotic spindle
F0097100molecular_functionsupercoiled DNA binding
F0140078molecular_functionclass I DNA-(apurinic or apyrimidinic site) endonuclease activity
F0140297molecular_functionDNA-binding transcription factor binding
F1901224biological_processpositive regulation of non-canonical NF-kappaB signal transduction
F1902231biological_processpositive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
F1905053biological_processpositive regulation of base-excision repair
F1990904cellular_componentribonucleoprotein complex
F2001235biological_processpositive regulation of apoptotic signaling pathway
F2001272biological_processpositive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
G0000082biological_processG1/S transition of mitotic cell cycle
G0000278biological_processmitotic cell cycle
G0001890biological_processplacenta development
G0002181biological_processcytoplasmic translation
G0002309biological_processT cell proliferation involved in immune response
G0003723molecular_functionRNA binding
G0003735molecular_functionstructural constituent of ribosome
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005654cellular_componentnucleoplasm
G0005730cellular_componentnucleolus
G0005737cellular_componentcytoplasm
G0005783cellular_componentendoplasmic reticulum
G0005829cellular_componentcytosol
G0005840cellular_componentribosome
G0006364biological_processrRNA processing
G0006412biological_processtranslation
G0006924biological_processactivation-induced cell death of T cells
G0007369biological_processgastrulation
G0008284biological_processpositive regulation of cell population proliferation
G0015935cellular_componentsmall ribosomal subunit
G0016020cellular_componentmembrane
G0019901molecular_functionprotein kinase binding
G0022605biological_processmammalian oogenesis stage
G0022626cellular_componentcytosolic ribosome
G0022627cellular_componentcytosolic small ribosomal subunit
G0030425cellular_componentdendrite
G0031929biological_processTOR signaling
G0032040cellular_componentsmall-subunit processome
G0033077biological_processT cell differentiation in thymus
G0036464cellular_componentcytoplasmic ribonucleoprotein granule
G0042274biological_processribosomal small subunit biogenesis
G0042593biological_processglucose homeostasis
G0043065biological_processpositive regulation of apoptotic process
G0043066biological_processnegative regulation of apoptotic process
G0044297cellular_componentcell body
G0048471cellular_componentperinuclear region of cytoplasm
G0048821biological_processerythrocyte development
G1990904cellular_componentribonucleoprotein complex
H0001843biological_processneural tube closure
H0002181biological_processcytoplasmic translation
H0003723molecular_functionRNA binding
H0003730molecular_functionmRNA 3'-UTR binding
H0003735molecular_functionstructural constituent of ribosome
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0005730cellular_componentnucleolus
H0005737cellular_componentcytoplasm
H0005783cellular_componentendoplasmic reticulum
H0005813cellular_componentcentrosome
H0005829cellular_componentcytosol
H0005840cellular_componentribosome
H0005856cellular_componentcytoskeleton
H0005925cellular_componentfocal adhesion
H0006364biological_processrRNA processing
H0006412biological_processtranslation
H0010628biological_processpositive regulation of gene expression
H0014033biological_processneural crest cell differentiation
H0016020cellular_componentmembrane
H0019901molecular_functionprotein kinase binding
H0022626cellular_componentcytosolic ribosome
H0022627cellular_componentcytosolic small ribosomal subunit
H0030686cellular_component90S preribosome
H0032040cellular_componentsmall-subunit processome
H0032991cellular_componentprotein-containing complex
H0042274biological_processribosomal small subunit biogenesis
H0045202cellular_componentsynapse
H0048027molecular_functionmRNA 5'-UTR binding
H0050821biological_processprotein stabilization
H1902255biological_processpositive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
H1904667biological_processnegative regulation of ubiquitin protein ligase activity
H1990904cellular_componentribonucleoprotein complex
H1990948molecular_functionubiquitin ligase inhibitor activity
H2000059biological_processnegative regulation of ubiquitin-dependent protein catabolic process
I0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
I0002181biological_processcytoplasmic translation
I0003723molecular_functionRNA binding
I0003735molecular_functionstructural constituent of ribosome
I0005515molecular_functionprotein binding
I0005634cellular_componentnucleus
I0005654cellular_componentnucleoplasm
I0005730cellular_componentnucleolus
I0005737cellular_componentcytoplasm
I0005783cellular_componentendoplasmic reticulum
I0005829cellular_componentcytosol
I0005840cellular_componentribosome
I0005925cellular_componentfocal adhesion
I0006412biological_processtranslation
I0016020cellular_componentmembrane
I0022626cellular_componentcytosolic ribosome
I0022627cellular_componentcytosolic small ribosomal subunit
I0032040cellular_componentsmall-subunit processome
I0042274biological_processribosomal small subunit biogenesis
I0070062cellular_componentextracellular exosome
I1990904cellular_componentribonucleoprotein complex
J0002181biological_processcytoplasmic translation
J0003723molecular_functionRNA binding
J0003735molecular_functionstructural constituent of ribosome
J0005515molecular_functionprotein binding
J0005634cellular_componentnucleus
J0005654cellular_componentnucleoplasm
J0005730cellular_componentnucleolus
J0005737cellular_componentcytoplasm
J0005829cellular_componentcytosol
J0005840cellular_componentribosome
J0005925cellular_componentfocal adhesion
J0006412biological_processtranslation
J0006417biological_processregulation of translation
J0008284biological_processpositive regulation of cell population proliferation
J0015935cellular_componentsmall ribosomal subunit
J0016020cellular_componentmembrane
J0019843molecular_functionrRNA binding
J0022626cellular_componentcytosolic ribosome
J0022627cellular_componentcytosolic small ribosomal subunit
J0032040cellular_componentsmall-subunit processome
J0042274biological_processribosomal small subunit biogenesis
J0043226cellular_componentorganelle
J0045182molecular_functiontranslation regulator activity
J0045202cellular_componentsynapse
J0070062cellular_componentextracellular exosome
J1990904cellular_componentribonucleoprotein complex
K0000028biological_processribosomal small subunit assembly
K0002181biological_processcytoplasmic translation
K0003723molecular_functionRNA binding
K0003729molecular_functionmRNA binding
K0003735molecular_functionstructural constituent of ribosome
K0005515molecular_functionprotein binding
K0005634cellular_componentnucleus
K0005654cellular_componentnucleoplasm
K0005730cellular_componentnucleolus
K0005737cellular_componentcytoplasm
K0005829cellular_componentcytosol
K0005840cellular_componentribosome
K0005925cellular_componentfocal adhesion
K0006412biological_processtranslation
K0006413biological_processtranslational initiation
K0006450biological_processregulation of translational fidelity
K0015935cellular_componentsmall ribosomal subunit
K0016020cellular_componentmembrane
K0019843molecular_functionrRNA binding
K0022626cellular_componentcytosolic ribosome
K0022627cellular_componentcytosolic small ribosomal subunit
K0032040cellular_componentsmall-subunit processome
K0042274biological_processribosomal small subunit biogenesis
K0045202cellular_componentsynapse
K0070062cellular_componentextracellular exosome
K1990904cellular_componentribonucleoprotein complex
L0002181biological_processcytoplasmic translation
L0003723molecular_functionRNA binding
L0003735molecular_functionstructural constituent of ribosome
L0005515molecular_functionprotein binding
L0005634cellular_componentnucleus
L0005654cellular_componentnucleoplasm
L0005730cellular_componentnucleolus
L0005737cellular_componentcytoplasm
L0005829cellular_componentcytosol
L0005840cellular_componentribosome
L0005925cellular_componentfocal adhesion
L0006412biological_processtranslation
L0016020cellular_componentmembrane
L0019843molecular_functionrRNA binding
L0022626cellular_componentcytosolic ribosome
L0022627cellular_componentcytosolic small ribosomal subunit
L0032040cellular_componentsmall-subunit processome
L0042274biological_processribosomal small subunit biogenesis
L0045202cellular_componentsynapse
L0070062cellular_componentextracellular exosome
L1990904cellular_componentribonucleoprotein complex
M0002181biological_processcytoplasmic translation
M0003723molecular_functionRNA binding
M0003735molecular_functionstructural constituent of ribosome
M0005515molecular_functionprotein binding
M0005634cellular_componentnucleus
M0005654cellular_componentnucleoplasm
M0005730cellular_componentnucleolus
M0005737cellular_componentcytoplasm
M0005829cellular_componentcytosol
M0005840cellular_componentribosome
M0005925cellular_componentfocal adhesion
M0006412biological_processtranslation
M0016020cellular_componentmembrane
M0022626cellular_componentcytosolic ribosome
M0022627cellular_componentcytosolic small ribosomal subunit
M1990904cellular_componentribonucleoprotein complex
N0002181biological_processcytoplasmic translation
N0003723molecular_functionRNA binding
N0003729molecular_functionmRNA binding
N0003735molecular_functionstructural constituent of ribosome
N0005515molecular_functionprotein binding
N0005634cellular_componentnucleus
N0005654cellular_componentnucleoplasm
N0005730cellular_componentnucleolus
N0005737cellular_componentcytoplasm
N0005829cellular_componentcytosol
N0005840cellular_componentribosome
N0005925cellular_componentfocal adhesion
N0006412biological_processtranslation
N0014069cellular_componentpostsynaptic density
N0016020cellular_componentmembrane
N0022626cellular_componentcytosolic ribosome
N0022627cellular_componentcytosolic small ribosomal subunit
N0032040cellular_componentsmall-subunit processome
N0033119biological_processnegative regulation of RNA splicing
N0042274biological_processribosomal small subunit biogenesis
N0048027molecular_functionmRNA 5'-UTR binding
N0070062cellular_componentextracellular exosome
N0070181molecular_functionsmall ribosomal subunit rRNA binding
N1990904cellular_componentribonucleoprotein complex
O0002181biological_processcytoplasmic translation
O0003723molecular_functionRNA binding
O0003735molecular_functionstructural constituent of ribosome
O0005515molecular_functionprotein binding
O0005634cellular_componentnucleus
O0005654cellular_componentnucleoplasm
O0005730cellular_componentnucleolus
O0005737cellular_componentcytoplasm
O0005794cellular_componentGolgi apparatus
O0005829cellular_componentcytosol
O0005840cellular_componentribosome
O0006412biological_processtranslation
O0016020cellular_componentmembrane
O0022626cellular_componentcytosolic ribosome
O0022627cellular_componentcytosolic small ribosomal subunit
O0032040cellular_componentsmall-subunit processome
O0042274biological_processribosomal small subunit biogenesis
O0043231cellular_componentintracellular membrane-bounded organelle
O0090263biological_processpositive regulation of canonical Wnt signaling pathway
O1990145biological_processmaintenance of translational fidelity
O1990904cellular_componentribonucleoprotein complex
P0000028biological_processribosomal small subunit assembly
P0000122biological_processnegative regulation of transcription by RNA polymerase II
P0002181biological_processcytoplasmic translation
P0003723molecular_functionRNA binding
P0003735molecular_functionstructural constituent of ribosome
P0005515molecular_functionprotein binding
P0005634cellular_componentnucleus
P0005654cellular_componentnucleoplasm
P0005730cellular_componentnucleolus
P0005737cellular_componentcytoplasm
P0005829cellular_componentcytosol
P0005840cellular_componentribosome
P0005925cellular_componentfocal adhesion
P0006412biological_processtranslation
P0006417biological_processregulation of translation
P0014069cellular_componentpostsynaptic density
P0015935cellular_componentsmall ribosomal subunit
P0016020cellular_componentmembrane
P0022626cellular_componentcytosolic ribosome
P0022627cellular_componentcytosolic small ribosomal subunit
P0030218biological_processerythrocyte differentiation
P0030490biological_processmaturation of SSU-rRNA
P0032040cellular_componentsmall-subunit processome
P0042274biological_processribosomal small subunit biogenesis
P0045182molecular_functiontranslation regulator activity
P0045202cellular_componentsynapse
P0048027molecular_functionmRNA 5'-UTR binding
P0070062cellular_componentextracellular exosome
P1990904cellular_componentribonucleoprotein complex
Q0000028biological_processribosomal small subunit assembly
Q0000056biological_processribosomal small subunit export from nucleus
Q0001649biological_processosteoblast differentiation
Q0002181biological_processcytoplasmic translation
Q0003677molecular_functionDNA binding
Q0003723molecular_functionRNA binding
Q0003735molecular_functionstructural constituent of ribosome
Q0005515molecular_functionprotein binding
Q0005634cellular_componentnucleus
Q0005654cellular_componentnucleoplasm
Q0005737cellular_componentcytoplasm
Q0005829cellular_componentcytosol
Q0005840cellular_componentribosome
Q0005925cellular_componentfocal adhesion
Q0006364biological_processrRNA processing
Q0006412biological_processtranslation
Q0015935cellular_componentsmall ribosomal subunit
Q0016020cellular_componentmembrane
Q0022626cellular_componentcytosolic ribosome
Q0022627cellular_componentcytosolic small ribosomal subunit
Q0042274biological_processribosomal small subunit biogenesis
Q0045202cellular_componentsynapse
Q0097371molecular_functionMDM2/MDM4 family protein binding
Q0097421biological_processliver regeneration
Q1901798biological_processpositive regulation of signal transduction by p53 class mediator
Q1990904cellular_componentribonucleoprotein complex
Q1990948molecular_functionubiquitin ligase inhibitor activity
R0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
R0002181biological_processcytoplasmic translation
R0003723molecular_functionRNA binding
R0003735molecular_functionstructural constituent of ribosome
R0005515molecular_functionprotein binding
R0005634cellular_componentnucleus
R0005654cellular_componentnucleoplasm
R0005730cellular_componentnucleolus
R0005737cellular_componentcytoplasm
R0005829cellular_componentcytosol
R0005840cellular_componentribosome
R0005925cellular_componentfocal adhesion
R0006364biological_processrRNA processing
R0006412biological_processtranslation
R0015935cellular_componentsmall ribosomal subunit
R0016020cellular_componentmembrane
R0022626cellular_componentcytosolic ribosome
R0022627cellular_componentcytosolic small ribosomal subunit
R0032040cellular_componentsmall-subunit processome
R0042274biological_processribosomal small subunit biogenesis
R0045202cellular_componentsynapse
R0070062cellular_componentextracellular exosome
R1990830biological_processcellular response to leukemia inhibitory factor
R1990904cellular_componentribonucleoprotein complex
S0002181biological_processcytoplasmic translation
S0003723molecular_functionRNA binding
S0003735molecular_functionstructural constituent of ribosome
S0005634cellular_componentnucleus
S0005654cellular_componentnucleoplasm
S0005730cellular_componentnucleolus
S0005737cellular_componentcytoplasm
S0005829cellular_componentcytosol
S0005840cellular_componentribosome
S0005925cellular_componentfocal adhesion
S0006364biological_processrRNA processing
S0006412biological_processtranslation
S0006413biological_processtranslational initiation
S0016020cellular_componentmembrane
S0022626cellular_componentcytosolic ribosome
S0022627cellular_componentcytosolic small ribosomal subunit
S0032040cellular_componentsmall-subunit processome
S0034101biological_processerythrocyte homeostasis
S0042274biological_processribosomal small subunit biogenesis
S0045202cellular_componentsynapse
S1990904cellular_componentribonucleoprotein complex
T0002181biological_processcytoplasmic translation
T0003676molecular_functionnucleic acid binding
T0003723molecular_functionRNA binding
T0003735molecular_functionstructural constituent of ribosome
T0005515molecular_functionprotein binding
T0005634cellular_componentnucleus
T0005654cellular_componentnucleoplasm
T0005737cellular_componentcytoplasm
T0005829cellular_componentcytosol
T0005840cellular_componentribosome
T0005925cellular_componentfocal adhesion
T0006412biological_processtranslation
T0014069cellular_componentpostsynaptic density
T0015935cellular_componentsmall ribosomal subunit
T0016020cellular_componentmembrane
T0019843molecular_functionrRNA binding
T0022626cellular_componentcytosolic ribosome
T0022627cellular_componentcytosolic small ribosomal subunit
T0045202cellular_componentsynapse
T0070062cellular_componentextracellular exosome
T1990904cellular_componentribonucleoprotein complex
U0000028biological_processribosomal small subunit assembly
U0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
U0002181biological_processcytoplasmic translation
U0002548biological_processmonocyte chemotaxis
U0003723molecular_functionRNA binding
U0003735molecular_functionstructural constituent of ribosome
U0005515molecular_functionprotein binding
U0005634cellular_componentnucleus
U0005654cellular_componentnucleoplasm
U0005730cellular_componentnucleolus
U0005737cellular_componentcytoplasm
U0005829cellular_componentcytosol
U0005840cellular_componentribosome
U0005925cellular_componentfocal adhesion
U0006364biological_processrRNA processing
U0006412biological_processtranslation
U0007000biological_processnucleolus organization
U0009991biological_processobsolete response to extracellular stimulus
U0014069cellular_componentpostsynaptic density
U0016020cellular_componentmembrane
U0017134molecular_functionfibroblast growth factor binding
U0019901molecular_functionprotein kinase binding
U0022626cellular_componentcytosolic ribosome
U0022627cellular_componentcytosolic small ribosomal subunit
U0030218biological_processerythrocyte differentiation
U0030490biological_processmaturation of SSU-rRNA
U0031640biological_processkilling of cells of another organism
U0032040cellular_componentsmall-subunit processome
U0042274biological_processribosomal small subunit biogenesis
U0042802molecular_functionidentical protein binding
U0050829biological_processdefense response to Gram-negative bacterium
U0051272biological_processobsolete positive regulation of cellular component movement
U0060265biological_processpositive regulation of respiratory burst involved in inflammatory response
U0060266biological_processnegative regulation of respiratory burst involved in inflammatory response
U0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
U0070062cellular_componentextracellular exosome
U1990904cellular_componentribonucleoprotein complex
V0002181biological_processcytoplasmic translation
V0003723molecular_functionRNA binding
V0003735molecular_functionstructural constituent of ribosome
V0005515molecular_functionprotein binding
V0005654cellular_componentnucleoplasm
V0005737cellular_componentcytoplasm
V0005829cellular_componentcytosol
V0005840cellular_componentribosome
V0006412biological_processtranslation
V0015935cellular_componentsmall ribosomal subunit
V0016020cellular_componentmembrane
V0022626cellular_componentcytosolic ribosome
V0022627cellular_componentcytosolic small ribosomal subunit
V0045202cellular_componentsynapse
V0070062cellular_componentextracellular exosome
V0097371molecular_functionMDM2/MDM4 family protein binding
V1901798biological_processpositive regulation of signal transduction by p53 class mediator
V1990904cellular_componentribonucleoprotein complex
V1990948molecular_functionubiquitin ligase inhibitor activity
W0002181biological_processcytoplasmic translation
W0003723molecular_functionRNA binding
W0003735molecular_functionstructural constituent of ribosome
W0005515molecular_functionprotein binding
W0005634cellular_componentnucleus
W0005654cellular_componentnucleoplasm
W0005730cellular_componentnucleolus
W0005737cellular_componentcytoplasm
W0005829cellular_componentcytosol
W0005840cellular_componentribosome
W0006412biological_processtranslation
W0008284biological_processpositive regulation of cell population proliferation
W0009615biological_processresponse to virus
W0016020cellular_componentmembrane
W0022626cellular_componentcytosolic ribosome
W0022627cellular_componentcytosolic small ribosomal subunit
W0032040cellular_componentsmall-subunit processome
W0042274biological_processribosomal small subunit biogenesis
W0045202cellular_componentsynapse
W0045787biological_processpositive regulation of cell cycle
W0070062cellular_componentextracellular exosome
W1990904cellular_componentribonucleoprotein complex
X0002181biological_processcytoplasmic translation
X0003723molecular_functionRNA binding
X0003735molecular_functionstructural constituent of ribosome
X0005515molecular_functionprotein binding
X0005634cellular_componentnucleus
X0005654cellular_componentnucleoplasm
X0005730cellular_componentnucleolus
X0005737cellular_componentcytoplasm
X0005783cellular_componentendoplasmic reticulum
X0005791cellular_componentrough endoplasmic reticulum
X0005829cellular_componentcytosol
X0005840cellular_componentribosome
X0006412biological_processtranslation
X0015935cellular_componentsmall ribosomal subunit
X0016020cellular_componentmembrane
X0022626cellular_componentcytosolic ribosome
X0022627cellular_componentcytosolic small ribosomal subunit
X0032040cellular_componentsmall-subunit processome
X0034063biological_processstress granule assembly
X0042274biological_processribosomal small subunit biogenesis
X0045202cellular_componentsynapse
X1990145biological_processmaintenance of translational fidelity
X1990904cellular_componentribonucleoprotein complex
Y0002181biological_processcytoplasmic translation
Y0003723molecular_functionRNA binding
Y0003735molecular_functionstructural constituent of ribosome
Y0005634cellular_componentnucleus
Y0005654cellular_componentnucleoplasm
Y0005730cellular_componentnucleolus
Y0005737cellular_componentcytoplasm
Y0005783cellular_componentendoplasmic reticulum
Y0005829cellular_componentcytosol
Y0005840cellular_componentribosome
Y0006364biological_processrRNA processing
Y0006412biological_processtranslation
Y0015935cellular_componentsmall ribosomal subunit
Y0016020cellular_componentmembrane
Y0022626cellular_componentcytosolic ribosome
Y0022627cellular_componentcytosolic small ribosomal subunit
Y0031369molecular_functiontranslation initiation factor binding
Y0032040cellular_componentsmall-subunit processome
Y0034101biological_processerythrocyte homeostasis
Y0042274biological_processribosomal small subunit biogenesis
Y0044391cellular_componentribosomal subunit
Y1990904cellular_componentribonucleoprotein complex
Z0000447biological_processendonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Z0000461biological_processendonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Z0002181biological_processcytoplasmic translation
Z0003723molecular_functionRNA binding
Z0003735molecular_functionstructural constituent of ribosome
Z0005515molecular_functionprotein binding
Z0005654cellular_componentnucleoplasm
Z0005737cellular_componentcytoplasm
Z0005783cellular_componentendoplasmic reticulum
Z0005791cellular_componentrough endoplasmic reticulum
Z0005829cellular_componentcytosol
Z0005840cellular_componentribosome
Z0006412biological_processtranslation
Z0015935cellular_componentsmall ribosomal subunit
Z0022626cellular_componentcytosolic ribosome
Z0022627cellular_componentcytosolic small ribosomal subunit
Z0045202cellular_componentsynapse
Z1990904cellular_componentribonucleoprotein complex
a0002181biological_processcytoplasmic translation
a0003723molecular_functionRNA binding
a0003735molecular_functionstructural constituent of ribosome
a0005515molecular_functionprotein binding
a0005634cellular_componentnucleus
a0005654cellular_componentnucleoplasm
a0005730cellular_componentnucleolus
a0005737cellular_componentcytoplasm
a0005829cellular_componentcytosol
a0005840cellular_componentribosome
a0006364biological_processrRNA processing
a0006412biological_processtranslation
a0014069cellular_componentpostsynaptic density
a0015935cellular_componentsmall ribosomal subunit
a0022626cellular_componentcytosolic ribosome
a0022627cellular_componentcytosolic small ribosomal subunit
a0042274biological_processribosomal small subunit biogenesis
a0045202cellular_componentsynapse
a0070062cellular_componentextracellular exosome
a1990904cellular_componentribonucleoprotein complex
b0000028biological_processribosomal small subunit assembly
b0002181biological_processcytoplasmic translation
b0003677molecular_functionDNA binding
b0003723molecular_functionRNA binding
b0003735molecular_functionstructural constituent of ribosome
b0005515molecular_functionprotein binding
b0005634cellular_componentnucleus
b0005654cellular_componentnucleoplasm
b0005730cellular_componentnucleolus
b0005737cellular_componentcytoplasm
b0005829cellular_componentcytosol
b0005840cellular_componentribosome
b0006364biological_processrRNA processing
b0006412biological_processtranslation
b0008270molecular_functionzinc ion binding
b0014069cellular_componentpostsynaptic density
b0022626cellular_componentcytosolic ribosome
b0022627cellular_componentcytosolic small ribosomal subunit
b0032040cellular_componentsmall-subunit processome
b0042274biological_processribosomal small subunit biogenesis
b0046872molecular_functionmetal ion binding
b1990904cellular_componentribonucleoprotein complex
c0002181biological_processcytoplasmic translation
c0003723molecular_functionRNA binding
c0003729molecular_functionmRNA binding
c0003735molecular_functionstructural constituent of ribosome
c0005515molecular_functionprotein binding
c0005654cellular_componentnucleoplasm
c0005737cellular_componentcytoplasm
c0005783cellular_componentendoplasmic reticulum
c0005791cellular_componentrough endoplasmic reticulum
c0005829cellular_componentcytosol
c0005840cellular_componentribosome
c0006412biological_processtranslation
c0015935cellular_componentsmall ribosomal subunit
c0016020cellular_componentmembrane
c0022627cellular_componentcytosolic small ribosomal subunit
c0033119biological_processnegative regulation of RNA splicing
c0045202cellular_componentsynapse
c0045296molecular_functioncadherin binding
c0070062cellular_componentextracellular exosome
c0098556cellular_componentcytoplasmic side of rough endoplasmic reticulum membrane
c1990904cellular_componentribonucleoprotein complex
d0000028biological_processribosomal small subunit assembly
d0002181biological_processcytoplasmic translation
d0003723molecular_functionRNA binding
d0003735molecular_functionstructural constituent of ribosome
d0005515molecular_functionprotein binding
d0005634cellular_componentnucleus
d0005654cellular_componentnucleoplasm
d0005730cellular_componentnucleolus
d0005737cellular_componentcytoplasm
d0005783cellular_componentendoplasmic reticulum
d0005791cellular_componentrough endoplasmic reticulum
d0005829cellular_componentcytosol
d0005840cellular_componentribosome
d0006364biological_processrRNA processing
d0006412biological_processtranslation
d0015935cellular_componentsmall ribosomal subunit
d0022627cellular_componentcytosolic small ribosomal subunit
d0030490biological_processmaturation of SSU-rRNA
d0032040cellular_componentsmall-subunit processome
d0042254biological_processribosome biogenesis
d0042274biological_processribosomal small subunit biogenesis
d0045202cellular_componentsynapse
d0070062cellular_componentextracellular exosome
d0098556cellular_componentcytoplasmic side of rough endoplasmic reticulum membrane
d1990904cellular_componentribonucleoprotein complex
e0003735molecular_functionstructural constituent of ribosome
e0005840cellular_componentribosome
e0006412biological_processtranslation
f0002181biological_processcytoplasmic translation
f0003735molecular_functionstructural constituent of ribosome
f0005654cellular_componentnucleoplasm
f0005737cellular_componentcytoplasm
f0005783cellular_componentendoplasmic reticulum
f0005791cellular_componentrough endoplasmic reticulum
f0005829cellular_componentcytosol
f0005840cellular_componentribosome
f0005925cellular_componentfocal adhesion
f0006412biological_processtranslation
f0008270molecular_functionzinc ion binding
f0015935cellular_componentsmall ribosomal subunit
f0022627cellular_componentcytosolic small ribosomal subunit
f0046872molecular_functionmetal ion binding
f0070062cellular_componentextracellular exosome
f0098556cellular_componentcytoplasmic side of rough endoplasmic reticulum membrane
f1990904cellular_componentribonucleoprotein complex
g0002181biological_processcytoplasmic translation
g0003723molecular_functionRNA binding
g0003735molecular_functionstructural constituent of ribosome
g0005515molecular_functionprotein binding
g0005615cellular_componentextracellular space
g0005634cellular_componentnucleus
g0005654cellular_componentnucleoplasm
g0005730cellular_componentnucleolus
g0005737cellular_componentcytoplasm
g0005741cellular_componentmitochondrial outer membrane
g0005789cellular_componentendoplasmic reticulum membrane
g0005829cellular_componentcytosol
g0005840cellular_componentribosome
g0005886cellular_componentplasma membrane
g0006412biological_processtranslation
g0010008cellular_componentendosome membrane
g0016020cellular_componentmembrane
g0016567biological_processprotein ubiquitination
g0019941biological_processmodification-dependent protein catabolic process
g0022626cellular_componentcytosolic ribosome
g0022627cellular_componentcytosolic small ribosomal subunit
g0030666cellular_componentendocytic vesicle membrane
g0031386molecular_functionprotein tag activity
g0031625molecular_functionubiquitin protein ligase binding
g0031982cellular_componentvesicle
g0032040cellular_componentsmall-subunit processome
g0045202cellular_componentsynapse
g0046872molecular_functionmetal ion binding
g0070062cellular_componentextracellular exosome
g1990904cellular_componentribonucleoprotein complex
h0002181biological_processcytoplasmic translation
h0003723molecular_functionRNA binding
h0003730molecular_functionmRNA 3'-UTR binding
h0003735molecular_functionstructural constituent of ribosome
h0005515molecular_functionprotein binding
h0005737cellular_componentcytoplasm
h0005783cellular_componentendoplasmic reticulum
h0005829cellular_componentcytosol
h0005840cellular_componentribosome
h0006412biological_processtranslation
h0022625cellular_componentcytosolic large ribosomal subunit
h0048027molecular_functionmRNA 5'-UTR binding
h1990904cellular_componentribonucleoprotein complex
j0001891cellular_componentphagocytic cup
j0001934biological_processpositive regulation of protein phosphorylation
j0002181biological_processcytoplasmic translation
j0003723molecular_functionRNA binding
j0005080molecular_functionprotein kinase C binding
j0005102molecular_functionsignaling receptor binding
j0005515molecular_functionprotein binding
j0005634cellular_componentnucleus
j0005654cellular_componentnucleoplasm
j0005737cellular_componentcytoplasm
j0005739cellular_componentmitochondrion
j0005829cellular_componentcytosol
j0005840cellular_componentribosome
j0005886cellular_componentplasma membrane
j0006412biological_processtranslation
j0006417biological_processregulation of translation
j0006915biological_processapoptotic process
j0006919biological_processactivation of cysteine-type endopeptidase activity involved in apoptotic process
j0007049biological_processcell cycle
j0007369biological_processgastrulation
j0008047molecular_functionenzyme activator activity
j0008200molecular_functionion channel inhibitor activity
j0008656molecular_functioncysteine-type endopeptidase activator activity involved in apoptotic process
j0010629biological_processnegative regulation of gene expression
j0015935cellular_componentsmall ribosomal subunit
j0016020cellular_componentmembrane
j0016567biological_processprotein ubiquitination
j0017148biological_processnegative regulation of translation
j0019899molecular_functionenzyme binding
j0019903molecular_functionprotein phosphatase binding
j0022627cellular_componentcytosolic small ribosomal subunit
j0030178biological_processnegative regulation of Wnt signaling pathway
j0030292molecular_functionprotein tyrosine kinase inhibitor activity
j0030308biological_processnegative regulation of cell growth
j0030332molecular_functioncyclin binding
j0030335biological_processpositive regulation of cell migration
j0030425cellular_componentdendrite
j0030496cellular_componentmidbody
j0030971molecular_functionreceptor tyrosine kinase binding
j0031334biological_processpositive regulation of protein-containing complex assembly
j0032091biological_processnegative regulation of protein binding
j0032436biological_processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
j0032880biological_processregulation of protein localization
j0033137biological_processnegative regulation of peptidyl-serine phosphorylation
j0035591molecular_functionsignaling adaptor activity
j0042169molecular_functionSH2 domain binding
j0042803molecular_functionprotein homodimerization activity
j0042995cellular_componentcell projection
j0042998biological_processpositive regulation of Golgi to plasma membrane protein transport
j0043005cellular_componentneuron projection
j0043022molecular_functionribosome binding
j0043025cellular_componentneuronal cell body
j0043065biological_processpositive regulation of apoptotic process
j0043204cellular_componentperikaryon
j0043473biological_processpigmentation
j0043547biological_processpositive regulation of GTPase activity
j0044297cellular_componentcell body
j0045182molecular_functiontranslation regulator activity
j0045296molecular_functioncadherin binding
j0045879biological_processnegative regulation of smoothened signaling pathway
j0048471cellular_componentperinuclear region of cytoplasm
j0048511biological_processrhythmic process
j0050765biological_processnegative regulation of phagocytosis
j0051302biological_processregulation of cell division
j0051434molecular_functionBH3 domain binding
j0051726biological_processregulation of cell cycle
j0051898biological_processnegative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
j0051901biological_processpositive regulation of mitochondrial depolarization
j0060090molecular_functionmolecular adaptor activity
j0070062cellular_componentextracellular exosome
j0071333biological_processcellular response to glucose stimulus
j0071363biological_processcellular response to growth factor stimulus
j0072344biological_processrescue of stalled ribosome
j0106070biological_processregulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
j1900102biological_processnegative regulation of endoplasmic reticulum unfolded protein response
j1903751biological_processnegative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
j1990630cellular_componentIRE1-RACK1-PP2A complex
j1990904cellular_componentribonucleoprotein complex
j2000114biological_processregulation of establishment of cell polarity
j2000543biological_processpositive regulation of gastrulation
j2001244biological_processpositive regulation of intrinsic apoptotic signaling pathway
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue ZN c 201
ChainResidue
cCYS23
cCYS26
cCYS74
cCYS77

site_idAC2
Number of Residues4
Detailsbinding site for residue ZN f 201
ChainResidue
fCYS21
fCYS24
fCYS39
fCYS42

site_idAC3
Number of Residues6
Detailsbinding site for residue ZN g 500
ChainResidue
gVAL130
gPHE131
gCYS141
gGLY142
gLYS143
2U1310

Functional Information from PROSITE/UniProt
site_idPS00712
Number of Residues16
DetailsRIBOSOMAL_S17E Ribosomal protein S17e signature. IpSKkLRNkIAGYvTH
ChainResidueDetails
SILE41-HIS56

site_idPS00527
Number of Residues23
DetailsRIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsnrhglirkyg.LNMCRqCFR
ChainResidueDetails
fARG22-ARG44

site_idPS00628
Number of Residues20
DetailsRIBOSOMAL_S19E Ribosomal protein S19e signature. PshfsrgSksVaRrVLQaLE
ChainResidueDetails
UPRO89-GLU108

site_idPS00632
Number of Residues25
DetailsRIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVFKlglAkSihhARvLI
ChainResidueDetails
JLEU106-ILE130

site_idPS00323
Number of Residues25
DetailsRIBOSOMAL_S19 Ribosomal protein S19 signature. NGKtfnqveIkpemIGhyLGEFsiT
ChainResidueDetails
QASN98-THR122

site_idPS00056
Number of Residues13
DetailsRIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgEcRPLS
ChainResidueDetails
LGLY123-SER135

site_idPS00528
Number of Residues15
DetailsRIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRVAaPkhWmLdK
ChainResidueDetails
EHIS8-LYS22

site_idPS00361
Number of Residues16
DetailsRIBOSOMAL_S10 Ribosomal protein S10 signature. AkekNLkvkGPVrMPT
ChainResidueDetails
VALA43-THR58

site_idPS00646
Number of Residues14
DetailsRIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHfwGlrVRGQ
ChainResidueDetails
TARG121-GLN134

site_idPS00578
Number of Residues12
DetailsRIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM
ChainResidueDetails
GILE52-MET63

site_idPS00961
Number of Residues9
DetailsRIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL
ChainResidueDetails
dGLU60-LEU68

site_idPS00053
Number of Residues18
DetailsRIBOSOMAL_S8 Ribosomal protein S8 signature. GfiVLTTSaGIMdheeAR
ChainResidueDetails
WGLY100-ARG117

site_idPS01191
Number of Residues13
DetailsRIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVfEvSLaDL
ChainResidueDetails
CLEU62-LEU74

site_idPS00529
Number of Residues23
DetailsRIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKTtGFGmIYDSldyakknE
ChainResidueDetails
YPHE64-GLU86

site_idPS00052
Number of Residues27
DetailsRIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsMMmhgrnnGKKlmtvrIVkhA
ChainResidueDetails
KGLU70-ALA96

site_idPS00360
Number of Residues19
DetailsRIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvAQiyAirqSiSKAL
ChainResidueDetails
RGLY74-LEU92

site_idPS00055
Number of Residues8
DetailsRIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR
ChainResidueDetails
XLYS60-ARG67

site_idPS01168
Number of Residues33
DetailsRIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgCykittvFShAqtvvlCvgCStvLcqPtG
ChainResidueDetails
bLYS36-GLY68

site_idPS00054
Number of Residues23
DetailsRIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GMkIgrieDvTPiPSD
ChainResidueDetails
PLEU116-ASP138

site_idPS00299
Number of Residues26
DetailsUBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD
ChainResidueDetails
gLYS27-ASP52

site_idPS00362
Number of Residues31
DetailsRIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY
ChainResidueDetails
NVAL98-TYR128

site_idPS01193
Number of Residues20
DetailsRIBOSOMAL_S8E Ribosomal protein S8e signature. RrkTGGkrkpy.HkKrKyELG
ChainResidueDetails
IARG11-GLY30

site_idPS00548
Number of Residues37
DetailsRIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfvdGlMihSgdpVnyyVDtavrhvlLrqGvlG
ChainResidueDetails
FALA147-GLY183

site_idPS00962
Number of Residues12
DetailsRIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VlKFLAAGTHLG
ChainResidueDetails
BVAL15-GLY26

site_idPS00963
Number of Residues25
DetailsRIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlLVVtDpraDhqpLtEasyvNLP
ChainResidueDetails
BPRO119-PRO143

site_idPS00733
Number of Residues8
DetailsRIBOSOMAL_S26E Ribosomal protein S26e signature. YCVSCAIH
ChainResidueDetails
cTYR73-HIS80

site_idPS00948
Number of Residues14
DetailsRIBOSOMAL_S7E Ribosomal protein S7e signature. RLvRELEKKFSgKH
ChainResidueDetails
HARG78-HIS91

site_idPS00585
Number of Residues33
DetailsRIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAfvAIGDyn.GhVGlGvkcsk.EVat.AI
ChainResidueDetails
DGLY119-ILE151

site_idPS00996
Number of Residues9
DetailsRIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA
ChainResidueDetails
ZLEU11-ALA19

site_idPS01189
Number of Residues19
DetailsRIBOSOMAL_S12E Ribosomal protein S12e signature. ALQevLktAlihDGLarGI
ChainResidueDetails
OALA17-ILE35

site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSGswDgTLRLWDL
ChainResidueDetails
jALA78-LEU92
jILE120-THR134
jILE165-LEU179
jCYS207-LEU221

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsSITE: Cleavage; by PL-PRO => ECO:0000250|UniProtKB:P0C6V3
ChainResidueDetails
iGLY180
ULYS111

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: N-acetylthreonine; in Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed => ECO:0000269|Ref.9, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378
ChainResidueDetails
jTHR2
gARG72
bCYS56
bCYS59

site_idSWS_FT_FI3
Number of Residues3
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163
ChainResidueDetails
jTHR6
jTHR10
jTHR96

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphotyrosine; by ABL1 => ECO:0000305|PubMed:19423701
ChainResidueDetails
jTYR52
VLYS75
TLYS106
PLYS106

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
jLYS130
LSER110
MLYS139

site_idSWS_FT_FI6
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P68040
ChainResidueDetails
jLYS183
NLYS43
FARG67

site_idSWS_FT_FI7
Number of Residues1
DetailsMOD_RES: Phosphotyrosine => ECO:0000269|PubMed:11279199
ChainResidueDetails
jTYR228
gLYS113

site_idSWS_FT_FI8
Number of Residues1
DetailsMOD_RES: Phosphoserine; by viral VacV B1 kinase => ECO:0000269|PubMed:28636603, ECO:0007744|PubMed:23186163
ChainResidueDetails
jSER276
DLYS275

site_idSWS_FT_FI9
Number of Residues1
DetailsMOD_RES: Phosphothreonine; by viral VacV B1 kinase => ECO:0000269|PubMed:28636603
ChainResidueDetails
jTHR277
GSER247

site_idSWS_FT_FI10
Number of Residues2
DetailsMOD_RES: Phosphoserine; by viral VacV B1 kinase => ECO:0000269|PubMed:28636603
ChainResidueDetails
jSER278
jSER279

site_idSWS_FT_FI11
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P68040
ChainResidueDetails
jTHR316
gLYS48

site_idSWS_FT_FI12
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860
ChainResidueDetails
gLYS27

site_idSWS_FT_FI13
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:25752573, ECO:0000269|PubMed:25752577, ECO:0000269|PubMed:34239127
ChainResidueDetails
gLYS29

site_idSWS_FT_FI14
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577
ChainResidueDetails
gLYS33
FLYS202

site_idSWS_FT_FI15
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106
ChainResidueDetails
gLYS63
FLYS230

site_idSWS_FT_FI16
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
ChainResidueDetails
gGLY76

site_idSWS_FT_FI17
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36638793
ChainResidueDetails
gLYS107

218853

PDB entries from 2024-04-24

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