6ZEE

Structure of PP1(7-300) bound to Phactr1 (507-580) at pH8.4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (P, Q, B, A, I...)	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	polymer	299	34162.1	6	UniProt (P62136) Pfam (PF16891) Pfam (PF00149)	Homo sapiens (Human)	PP-1A
2	G, H, I, J, K... (W, X, D, C, U...)	Phosphatase and actin regulator	polymer	78	9212.4	6	UniProt (Q4VY12) Pfam (PF02755) UniProt (by SIFTS) (Q9C0D0)	Homo sapiens (Human)
3	AA, BC, CC, HA, IA... (Q, K, B, P, I...)	MANGANESE (II) ION	non-polymer		54.9	12	Chemie (MN)
4	AB, AC, BA, BB, CA... (A, I, Q, K, B...)	1,2-ETHANEDIOL	non-polymer		62.1	54	Chemie (EDO)
5	EC, IC, LC, MC, PC... (K, X, D, C, P)	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
6	GA, JC, KC, OC, PB... (Q, K, W, D, A...)	SULFATE ION	non-polymer		96.1	14	Chemie (SO4)
7	GB (A)	3,6,9,12,15,18-HEXAOXAICOSANE	non-polymer		294.4	1	Chemie (16P)
8	AD, BD, CD, DD, ED... (K, W, X, D, C...)	water	water		18.0	740	Chemie (HOH)

Sequence modifications

P, Q, B, A, I, K: 7 - 300 (UniProt: P62136)

PDB	External Database	Details
Gly 2	-	expression tag
His 3	-	expression tag
Met 4	-	expression tag
Gly 5	-	expression tag
Ser 6	-	expression tag

W, X, D, C, U, V: 508 - 580 (UniProt: Q4VY12)

PDB	External Database	Details
Gly 503	-	expression tag
Pro 504	-	expression tag
Leu 505	-	expression tag
Gly 506	-	expression tag
Ser 507	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	260247.2
Non-Polymers*	Number of molecules	87
	Total formula weight	6202.8
All*	Total formula weight	266450.0

*Water molecules are not included.