6Z3L
Repulsive Guidance Molecule C (RGMC, Hemojuvelin, HJV, HFE2) in complex with Growth Differentiation Factor 5 (GDF5)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Growth/differentiation factor 5 | polymer | 117 | 13405.5 | 1 | UniProt (P43026) Pfam (PF00019) In PDB | Homo sapiens (Human) | GDF-5,Bone morphogenetic protein 14,BMP-14,Cartilage-derived morphogenetic protein 1,CDMP-1,Lipopolysaccharide-associated protein 4,LPS-associated protein 4,Radotermin |
2 | B | Hemojuvelin | polymer | 122 | 12402.0 | 1 | UniProt (Q6ZVN8) Pfam (PF06535) In PDB | Homo sapiens (Human) | Hemochromatosis type 2 protein,Hemojuvelin BMP coreceptor,RGM domain family member C |
3 | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A: 387 - 501 (UniProt: P43026)
B: 36 - 145 (UniProt: Q6ZVN8)
PDB | External Database | Details |
---|---|---|
Met 385 | - | initiating methionine |
Lys 386 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Glu 33 | - | expression tag |
Thr 34 | - | expression tag |
Gly 35 | - | expression tag |
Gly 146 | - | expression tag |
Thr 147 | - | expression tag |
Lys 148 | - | expression tag |
His 149 | - | expression tag |
His 150 | - | expression tag |
His 151 | - | expression tag |
His 152 | - | expression tag |
His 153 | - | expression tag |
His 154 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 25807.5 | |
All* | Total formula weight | 25807.5 |