6Z2K
The structure of the tetrameric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C, E, K, I | Histone deacetylase 1 | polymer | 482 | 55178.9 | 4 | UniProt (Q13547) Pfam (PF00850) In PDB | Homo sapiens (Human) | HD1 |
2 | A, B, G, H | Deoxynucleotidyltransferase terminal-interacting protein 1 | polymer | 130 | 14381.3 | 4 | UniProt (Q9H147) Pfam (PF18192) In PDB | Homo sapiens (Human) | Terminal deoxynucleotidyltransferase-interacting factor 1,TdT-interacting factor 1 |
3 | F, D, L, J | Mitotic deacetylase-associated SANT domain protein | polymer | 173 | 19794.8 | 4 | UniProt (Q6PJG2) Pfam (PF01448) In PDB | Homo sapiens (Human) | ELM2 and SANT domain-containing protein 1 |
4 | C, E, K, I | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
5 | C, E, K, I | POTASSIUM ION | non-polymer | 39.1 | 8 | Chemie (K) | |||
6 | D, J, E, F | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 4 | Chemie (IHP) |
Sequence modifications
F, D, L, J: 717 - 887 (UniProt: Q6PJG2)
PDB | External Database | Details |
---|---|---|
Gly 715 | - | expression tag |
Ala 716 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 357419.9 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 3214.6 | |
All* | Total formula weight | 360634.4 |