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6Z2K

The structure of the tetrameric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1C, E, K, IHistone deacetylase 1polymer48255178.94UniProt (Q13547)
Pfam (PF00850)
In PDB
Homo sapiens (Human)HD1
2A, B, G, HDeoxynucleotidyltransferase terminal-interacting protein 1polymer13014381.34UniProt (Q9H147)
Pfam (PF18192)
In PDB
Homo sapiens (Human)Terminal deoxynucleotidyltransferase-interacting factor 1,TdT-interacting factor 1
3F, D, L, JMitotic deacetylase-associated SANT domain proteinpolymer17319794.84UniProt (Q6PJG2)
Pfam (PF01448)
In PDB
Homo sapiens (Human)ELM2 and SANT domain-containing protein 1
4C, E, K, IZINC IONnon-polymer65.44Chemie (ZN)
5C, E, K, IPOTASSIUM IONnon-polymer39.18Chemie (K)
6D, J, E, FINOSITOL HEXAKISPHOSPHATEnon-polymer660.04Chemie (IHP)
Sequence modifications
F, D, L, J: 717 - 887 (UniProt: Q6PJG2)
PDBExternal DatabaseDetails
Gly 715-expression tag
Ala 716-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight357419.9
Non-Polymers*Number of molecules16
Total formula weight3214.6
All*Total formula weight360634.4
*Water molecules are not included.

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PDB entries from 2024-07-10

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