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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6YXY

State B of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A1)		bL28mpolymer24128051.41UniProt (Q586A2)Trypanosoma brucei brucei
2B
(A2)		uL29mpolymer47154045.41UniProt (Q38EM7)
Pfam (PF06984)		Trypanosoma brucei brucei
3C
(A3)		uL30mpolymer21825218.41UniProt (Q38ED8)Trypanosoma brucei brucei
4D
(A5)		bL32mpolymer809745.71UniProt (Q584F4)Trypanosoma brucei brucei
5E
(A8)		bL35mpolymer18121661.51UniProt (D0A1K1)Trypanosoma brucei brucei
6F
(AA)		12S ribosomal RNApolymer1176373911.71GenBank (343546)Trypanosoma brucei brucei
7G
(BA)		mL67polymer83193569.31UniProt (Q386Z1)Trypanosoma brucei brucei
8H
(EA)		mt-EngApolymer57665528.31UniProt (Q57TZ4)
Pfam (PF01926)
Pfam (PF14714)		Trypanosoma brucei brucei
9I
(BB)		mL68polymer54162806.31UniProt (D0A135)Trypanosoma brucei brucei
10J
(EB)		mt-LAF2polymer75485715.31UniProt (D0A9G9)Trypanosoma brucei brucei
11K
(EC)		mt-LAF3polymer40646374.71UniProt (Q38FJ3)
Pfam (PF00849)		Trypanosoma brucei brucei
12L
(BD)		mL70polymer54762442.41Trypanosoma brucei brucei
13M
(ED)		mt-LAF4polymer61669460.41UniProt (Q385G9)Trypanosoma brucei brucei
14N
(AE)		uL3mpolymer47355073.71UniProt (Q580R4)
Pfam (PF00297)		Trypanosoma brucei brucei
15O
(BE)		mL71polymer44950313.81UniProt (Q57WG1)Trypanosoma brucei brucei
16P
(EE)		mt-LAF5polymer58667167.31UniProt (Q38DC9)
Pfam (PF00588)		Trypanosoma brucei brucei
17Q
(UE)		UNKpolymer332826.51Trypanosoma brucei brucei
18R
(AF)		uL4mpolymer45953156.71UniProt (D0A7A6)Trypanosoma brucei brucei
19S
(BF)		mL72polymer42649407.01UniProt (A0A3L6LA84)Trypanosoma brucei brucei
20T
(EF)		mt-LAF6polymer37340106.11UniProt (C9ZWD9)Trypanosoma brucei brucei
21U
(EG)		mt-LAF7polymer15618645.31UniProt (Q387S8)Trypanosoma brucei brucei
22V
(BH)		mL74polymer34939765.21UniProt (Q38AM5)Trypanosoma brucei brucei
23W
(EH)		mt-LAF8polymer63468905.01UniProt (Q57ZS6)Trypanosoma brucei brucei
24X
(AI)		bL9mpolymer26330729.31UniProt (Q57UC5)
Pfam (PF01281)		Trypanosoma brucei brucei
25Y
(BI)		mL75polymer34239770.51UniProt (D0A108)Trypanosoma brucei brucei
26Z
(EI)		MALSU1polymer34939553.51UniProt (Q584Y2)
Pfam (PF02410)		Trypanosoma brucei brucei
27AA
(UI)		UNKpolymer231975.41Trypanosoma brucei brucei
28BA
(BJ)		mL76polymer33339638.91UniProt (Q383M2)Trypanosoma brucei brucei
29CA
(EJ)		L0R8F8polymer11613444.61UniProt (Q57UQ1)Trypanosoma brucei brucei
30DA
(AK)		uL11mpolymer34240266.81UniProt (Q586R9)
Pfam (PF03946)
Pfam (PF00298)		Trypanosoma brucei brucei
31EA
(BK)		mL77polymer38643754.61UniProt (C9ZQR6)Trypanosoma brucei brucei
32FA, YA
(EK, ER)		mt-ACPpolymer14816550.82UniProt (Q57WW9)
Pfam (PF00550)		Trypanosoma brucei brucei
33GA
(UK)		UNKpolymer252145.61Trypanosoma brucei brucei
34HA
(BL)		mL78polymer31235104.51UniProt (Q389N4)Trypanosoma brucei brucei
35IA
(EL)		mt-LAF12polymer69177908.41UniProt (C9ZVC0)Trypanosoma brucei brucei
36JA
(UL)		UNKpolymer726145.61Trypanosoma brucei brucei
37KA
(EM)		Mtg1polymer45150416.51UniProt (Q38E75)
Pfam (PF01926)		Trypanosoma brucei brucei
38LA
(UM)		UNKpolymer8698.91Trypanosoma brucei brucei
39MA
(AN)		uL13mpolymer20224341.31UniProt (Q580D5)
Pfam (PF00572)		Trypanosoma brucei brucei
40NA
(BN)		mL80polymer30234883.31UniProt (C9ZQF0)Trypanosoma brucei brucei
41OA
(EN)		mt-LAF14polymer73182109.01UniProt (C9ZPS0)Trypanosoma brucei brucei
42PA
(AO)		uL14mpolymer21725133.61Trypanosoma brucei brucei
43QA
(BO)		mL81polymer26229284.51UniProt (Q385L5)Trypanosoma brucei brucei
44RA, TA
(EO, EP)		mt-LAF15apolymer31934621.42UniProt (C9ZMA6)Trypanosoma brucei brucei
45SA
(AP)		uL15mpolymer37443780.01UniProt (Q57U68)
Pfam (PF00828)		Trypanosoma brucei brucei
46UA
(BQ)		mL83polymer23125579.01UniProt (Q57WF8)
Pfam (PF00160)		Trypanosoma brucei bruceiPPIase
47VA
(EQ)		mt-EngBpolymer65571472.61UniProt (Q380Y8)
Pfam (PF01926)		Trypanosoma brucei brucei
48WA
(AR)		bL17mpolymer30135117.81UniProt (Q57YI7)
Pfam (PF01196)		Trypanosoma brucei brucei
49XA
(BR)		mL84polymer20524773.61UniProt (Q586A6)Trypanosoma brucei brucei
50ZA
(BS)		mL85polymer19822658.01UniProt (Q38FG8)Trypanosoma brucei brucei
51AB
(ES)		mt-LAF18polymer52458830.71UniProt (A0A3L6L1Y4)Trypanosoma brucei brucei
52BB
(AT)		bL19mpolymer14416931.51UniProt (Q4GZ98)Trypanosoma brucei brucei
53CB
(BT)		mL86polymer19122376.21UniProt (A0A3L6L8W0)Trypanosoma brucei brucei
54DB
(ET)		mt-LAF19polymer10212076.11UniProt (Q383S4)Trypanosoma brucei brucei
55EB
(AU)		bL20mpolymer21324393.91UniProt (Q383R2)Trypanosoma brucei brucei
56FB
(BU)		mL87polymer18522337.51UniProt (D0A7Z9)Trypanosoma brucei brucei
57GB
(EU)		mt-LAF20polymer566939.41Trypanosoma brucei brucei
58HB
(AV)		bL21mpolymer18820895.31UniProt (C9ZT11)Trypanosoma brucei brucei
59IB
(BV)		mL88polymer19022255.61UniProt (C9ZUW3)Trypanosoma brucei brucei
60JB
(AW)		uL22mpolymer27832083.31UniProt (C9ZSI8)Trypanosoma brucei brucei
61KB
(BW)		mL89polymer18822213.41UniProt (Q57WW5)Trypanosoma brucei brucei
62LB
(AX)		uL23mpolymer24628848.01UniProt (Q387G3)Trypanosoma brucei brucei
63MB
(BX)		mL90polymer19022123.41UniProt (Q585P1)
Pfam (PF00412)		Trypanosoma brucei brucei
64NB
(UX)		UNKpolymer18015336.91Trypanosoma brucei brucei
65OB
(AY)		uL24mpolymer37843999.01UniProt (C9ZK52)Trypanosoma brucei brucei
66PB
(BZ)		mL92polymer19020542.31UniProt (Q383Y4)
Pfam (PF00160)		Trypanosoma brucei bruceiPPIase
67QB
(Ba)		mL93polymer15318929.71UniProt (D0A4T0)Trypanosoma brucei brucei
68RB
(Bb)		mL94polymer16217831.01UniProt (Q38EP7)Trypanosoma brucei brucei
69SB
(Bc)		mL95polymer14617803.41UniProt (Q389K3)Trypanosoma brucei brucei
70TB
(Ae)		mL41polymer19722610.91UniProt (Q383U6)Trypanosoma brucei brucei
71UB
(Af)		mL42polymer18921602.61UniProt (Q383S1)Trypanosoma brucei brucei
72VB
(Bf)		mL98polymer11312968.61UniProt (Q388M2)Trypanosoma brucei brucei
73WB
(Ag)		mL43polymer26031300.41UniProt (Q583E5)
Pfam (PF05047)		Trypanosoma brucei brucei
74XB
(Bg)		mL99polymer10512335.01UniProt (Q587H8)Trypanosoma brucei brucei
75YB
(Bh)		mL100polymer9210600.41UniProt (A0A3L6L2V1)Trypanosoma brucei brucei
76ZB
(Bi)		mL101polymer24528455.81UniProt (Q4GZ80)Trypanosoma brucei brucei
77AC
(Al)		mL49polymer21824501.51UniProt (Q57Z82)Trypanosoma brucei brucei
78BC
(Ao)		mL52polymer1520167692.81UniProt (Q385V2)Trypanosoma brucei brucei
79CC
(Ap)		mL53polymer30935656.41UniProt (A0A3L6L3K9)Trypanosoma brucei brucei
80DC
(At)		mL63polymer15418213.91UniProt (C9ZU82)Trypanosoma brucei brucei
81EC
(Av)		mL64polymer24228546.01UniProt (D0A934)Trypanosoma brucei brucei
82FC, SD, XD, YD, ZD
(A5, EG, BX, Bh)		ZINC IONnon-polymer65.45Chemie (ZN)
83AD, BD, CD, DD, ED...
(AA, EA, EB, EQ)		MAGNESIUM IONnon-polymer24.333Chemie (MG)
84JD
(AA)		SPERMIDINEnon-polymer145.21Chemie (SPD)
85KD, ND, UD
(EA, EQ)		GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.23Chemie (GTP)
86MD, PD
(EA)		SODIUM IONnon-polymer23.02Chemie (NA)
87QD
(EB)		ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
88TD, WD
(EK, ER)		S-(2-{[N-(2-HYDROXY-4-{[HYDROXY(OXIDO)PHOSPHINO]OXY}-3,3-DIMETHYLBUTANOYL)-BETA-ALANYL]AMINO}ETHYL) DECANETHIOATEnon-polymer496.62Chemie (PM8)
89AE
(Av)		NICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.41Chemie (NAD)
90BE, CE, DE, EE
(EA, EB, EQ)		waterwater18.010Chemie (HOH)
Sequence modifications
A2: 1 - 471 (UniProt: Q38EM7)
PDBExternal DatabaseDetails
Gly 238Ala 238conflict
A3: 1 - 218 (UniProt: Q38ED8)
PDBExternal DatabaseDetails
Val 22Gly 22conflict
Ser 26Leu 26conflict
Asn 35Ser 35conflict
Unk 198Ala 198conflict
AA: 1 - 1176 (GenBank: 343546)
PDBExternal DatabaseDetails
N 1032A 2395conflict
N 1033U 2396conflict
N 1034U 2397conflict
N 1035G 2398conflict
N 1036U 2399conflict
N 1037U 2400conflict
N 1038C 2401conflict
N 1039A 2402conflict
N 1040U 2403conflict
N 1041C 2404conflict
N 1042A 2405conflict
N 1043A 2406conflict
N 1044A 2407conflict
N 1045A 2408conflict
N 1046U 2409conflict
N 1047A 2410conflict
N 1048G 2411conflict
N 1049U 2412conflict
BA: 1 - 831 (UniProt: Q386Z1)
PDBExternal DatabaseDetails
Cys 359Gly 359conflict
Pro 385Ser 385conflict
Ser 387Gly 387conflict
Ala 456Val 456conflict
Leu 520Arg 520conflict
EA: 1 - 576 (UniProt: Q57TZ4)
PDBExternal DatabaseDetails
Unk 12Arg 12conflict
EB: 1 - 754 (UniProt: D0A9G9)
PDBExternal DatabaseDetails
Ala 301Thr 301conflict
EC: 1 - 406 (UniProt: Q38FJ3)
PDBExternal DatabaseDetails
Unk 25His 25conflict
ED: 1 - 616 (UniProt: Q385G9)
PDBExternal DatabaseDetails
Arg 252Lys 252conflict
Unk 326Gly 326conflict
EE: 1 - 586 (UniProt: Q38DC9)
PDBExternal DatabaseDetails
Val 20Met 20conflict
Arg 27Lys 27conflict
Asp 337Gly 337conflict
Val 546Ala 546conflict
AF: 1 - 459 (UniProt: D0A7A6)
PDBExternal DatabaseDetails
Thr 12Ala 12conflict
EF: 1 - 373 (UniProt: C9ZWD9)
PDBExternal DatabaseDetails
Unk 47Glu 47conflict
Unk 48Val 48conflict
Unk 49Ala 49conflict
Unk 50Gln 50conflict
Unk 51Val 51conflict
Unk 52Thr 52conflict
EH: 1 - 634 (UniProt: Q57ZS6)
PDBExternal DatabaseDetails
Unk 166Gly 166conflict
Pro 485Ser 485conflict
Arg 495Lys 495conflict
AI: 1 - 263 (UniProt: Q57UC5)
PDBExternal DatabaseDetails
Unk 249Lys 249conflict
Unk 250Gly 250conflict
Unk 251Pro 251conflict
Unk 252Val 252conflict
Unk 253Lys 253conflict
Unk 254Gln 254conflict
Unk 255Arg 255conflict
Unk 256Lys 256conflict
Unk 257Ala 257conflict
Unk 258Arg 258conflict
BI: 1 - 342 (UniProt: D0A108)
PDBExternal DatabaseDetails
Asn 227Asp 227conflict
EI: 1 - 349 (UniProt: Q584Y2)
PDBExternal DatabaseDetails
Tyr 12Cys 12conflict
Pro 70Leu 70conflict
His 129Arg 129conflict
Ser 144Leu 144conflict
BJ: 1 - 333 (UniProt: Q383M2)
PDBExternal DatabaseDetails
Glu 329Ala 329conflict
AK: 1 - 342 (UniProt: Q586R9)
PDBExternal DatabaseDetails
Unk 327Ala 327conflict
BK: 1 - 386 (UniProt: C9ZQR6)
PDBExternal DatabaseDetails
Unk 33His 33conflict
Unk 60Pro 60conflict
Val 348Leu 348conflict
BL: 3 - 314 (UniProt: Q389N4)
PDBExternal DatabaseDetails
Tyr 77His 75conflict
Ala 218Thr 216conflict
Ser 292Asn 290conflict
EL: 1 - 691 (UniProt: C9ZVC0)
PDBExternal DatabaseDetails
Unk 104Ile 104conflict
Glu 108Gly 108conflict
Val 126Leu 126conflict
Ser 188Phe 188conflict
EM: 1 - 451 (UniProt: Q38E75)
PDBExternal DatabaseDetails
Unk 407Pro 407conflict
EN: 1 - 731 (UniProt: C9ZPS0)
PDBExternal DatabaseDetails
Glu 18Gly 18conflict
Lys 310Asn 310conflict
Cys 676Tyr 676conflict
BO: 1 - 262 (UniProt: Q385L5)
PDBExternal DatabaseDetails
Thr 30Ile 30conflict
Leu 123Met 123conflict
Pro 134Ser 134conflict
Asn 196Ser 196conflict
Ala 238Glu 238conflict
EQ: 1 - 656 (UniProt: Q380Y8)
PDBExternal DatabaseDetails
Cys 26Arg 26conflict
Ser 272Asn 272conflict
Ala 325Thr 325conflict
Ala 326Thr 326conflict
Unk 379Pro 379conflict
Ser 400Pro 400conflict
Arg 426Gln 426conflict
Glu 447Lys 447conflict
Unk 448Ser 448conflict
Ser 468Pro 468conflict
Ser 472Pro 472conflict
BS: 1 - 198 (UniProt: Q38FG8)
PDBExternal DatabaseDetails
Ile 45Val 45conflict
Unk 173Leu 173conflict
AX: 1 - 246 (UniProt: Q387G3)
PDBExternal DatabaseDetails
Tyr 126His 126conflict
AY: 1 - 378 (UniProt: C9ZK52)
PDBExternal DatabaseDetails
Glu 345Val 345conflict
Bi: 1 - 245 (UniProt: Q4GZ80)
PDBExternal DatabaseDetails
Met 143Ile 143conflict
Val 163Leu 163conflict
Ile 213Pro 213conflict
Ao: -1260 - 259 (UniProt: Q385V2)
PDBExternal DatabaseDetails
Gln -1239Arg 22conflict
Ala -1157Glu 104conflict
Ala -1105Val 156conflict
Gly -1062Ser 199conflict
His -879Tyr 382conflict
Unk -776His 485conflict
Unk -742Lys 519conflict
Glu -724Lys 537conflict
Unk -707Ser 554conflict
Glu -521Gly 740conflict
Arg -515Gln 746conflict
Leu -481Val 780conflict
Ala -214Val 1047conflict
Leu -175Val 1086conflict
-Leu 1249deletion
-Lys 1250deletion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains83
Total formula weight3248158.1
Non-Polymers*Number of molecules48
Total formula weight5053.7
All*Total formula weight3253211.7
*Water molecules are not included.

248335

PDB entries from 2026-01-28

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