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6YWT

Human OMPD-domain of UMPS (K314AcK) in complex with 6-hydroxy-UMP at 1.05 Angstroms resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Uridine 5'-monophosphate synthasepolymer26028372.81UniProt (P11172)
Pfam (PF00215)
Homo sapiens (Human)UMP synthase
2B
(A)
6-HYDROXYURIDINE-5'-PHOSPHATEnon-polymer340.21Chemie (BMP)
3C, D
(A)
PROLINEnon-polymer115.12Chemie (PRO)
4E
(A)
waterwater18.0333Chemie (HOH)
Sequence modifications
A: 224 - 480 (UniProt: P11172)
PDBExternal DatabaseDetails
Gly 221-expression tag
Ala 222-expression tag
Met 223-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28372.8
Non-Polymers*Number of molecules3
Total formula weight570.4
All*Total formula weight28943.3
*Water molecules are not included.

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PDB entries from 2025-11-12

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