6YPC
Crystal structure of the kinetochore subunits H/I/K/T/W penta-complex from S. cerevisiae at 2.9 angstroms
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (K) | Inner kinetochore subunit MCM22 | polymer | 110 | 12748.6 | 1 | UniProt (P47167) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | CENP-K homolog,Constitutive centromere-associated network protein MCM22,Minichromosome maintenance protein 22 |
| 2 | B (H) | Inner kinetochore subunit MCM16 | polymer | 46 | 5153.7 | 1 | UniProt (Q12262) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | CENP-H homolog,Constitutive centromere-associated network protein MCM16,Minichromosome maintenance protein 16 |
| 3 | C (T) | Inner kinetochore subunit CNN1 | polymer | 367 | 42154.6 | 1 | UniProt (P43618) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | CENP-T homolog,Co-purified with NNF1 protein 1,Constitutive centromere-associated network protein CNN1 |
| 4 | D (W) | Inner kinetochore subunit WIP1 | polymer | 89 | 10255.5 | 1 | UniProt (Q2V2P8) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | CENP-W homolog,Constitutive centromere-associated network protein WIP1,W-like protein 1 |
| 5 | E (I) | Inner kinetochore subunit CTF3 | polymer | 251 | 28856.7 | 1 | UniProt (Q12748) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | CENP-I homolog,Chromosome loss protein 3,Chromosome transmission fidelity protein 3,Constitutive centromere-associated network protein CTF3 |
| 6 | F, G, H (K, T, I) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
K: 131 - 239 (UniProt: P47167)
H: 137 - 181 (UniProt: Q12262)
T: 1 - 361 (UniProt: P43618)
I: 1 - 245 (UniProt: Q12748)
| PDB | External Database | Details |
|---|---|---|
| Met 130 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 136 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Glu 362 | - | expression tag |
| Asn 363 | - | expression tag |
| Leu 364 | - | expression tag |
| Tyr 365 | - | expression tag |
| Phe 366 | - | expression tag |
| Gln 367 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Glu 246 | - | expression tag |
| Asn 247 | - | expression tag |
| Leu 248 | - | expression tag |
| Tyr 249 | - | expression tag |
| Phe 250 | - | expression tag |
| Gln 251 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 99169.2 | |
| All* | Total formula weight | 99169.2 |
