6YPC
Crystal structure of the kinetochore subunits H/I/K/T/W penta-complex from S. cerevisiae at 2.9 angstroms
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| T | 0000775 | cellular_component | chromosome, centromeric region |
| T | 0000776 | cellular_component | kinetochore |
| T | 0005515 | molecular_function | protein binding |
| T | 0005634 | cellular_component | nucleus |
| T | 0005694 | cellular_component | chromosome |
| T | 0007059 | biological_process | chromosome segregation |
| T | 0019237 | molecular_function | centromeric DNA binding |
| T | 0044877 | molecular_function | protein-containing complex binding |
| T | 0051301 | biological_process | cell division |
| T | 1905560 | biological_process | negative regulation of kinetochore assembly |
| W | 0000775 | cellular_component | chromosome, centromeric region |
| W | 0000776 | cellular_component | kinetochore |
| W | 0005634 | cellular_component | nucleus |
| W | 0005694 | cellular_component | chromosome |
| W | 0007059 | biological_process | chromosome segregation |
| W | 0019237 | molecular_function | centromeric DNA binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylserine => ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| I | SER2 | |
| T | SER52 | |
| T | SER55 | |
| T | SER115 | |
| T | SER192 | |
| T | SER268 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by CDK1 and MPS1 => ECO:0000269|PubMed:22561345, ECO:0000269|PubMed:23334295 |
| Chain | Residue | Details |
| T | THR14 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by CDK1 and MPS1 => ECO:0000269|PubMed:22561345, ECO:0000269|PubMed:23334295 |
| Chain | Residue | Details |
| T | SER17 | |
| T | SER74 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine; by CDK1 => ECO:0000269|PubMed:23334295 |
| Chain | Residue | Details |
| T | THR21 | |
| T | THR42 | |
| T | THR191 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by CDK1 and MPS1 => ECO:0000269|PubMed:23334295 |
| Chain | Residue | Details |
| T | SER50 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine; by MPS1 => ECO:0000269|PubMed:23334295 |
| Chain | Residue | Details |
| T | THR53 | |
| T | THR86 | |
| T | THR88 | |
| T | THR134 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine; by CDK1 and MPS1 => ECO:0000269|PubMed:23334295 |
| Chain | Residue | Details |
| T | THR91 | |
| T | THR129 | |
| T | THR139 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by MPS1 => ECO:0000269|PubMed:23334295 |
| Chain | Residue | Details |
| T | SER135 | |
| T | SER153 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by MPS1 => ECO:0000269|PubMed:22561345, ECO:0000269|PubMed:23334295 |
| Chain | Residue | Details |
| T | THR174 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by CDK1 => ECO:0000269|PubMed:22561345, ECO:0000269|PubMed:23334295 |
| Chain | Residue | Details |
| T | SER177 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by MPS1 and IPL1 => ECO:0000269|PubMed:22561345 |
| Chain | Residue | Details |
| T | SER269 |
