6YK4
Structure of the AMPA receptor GluA2o ligand-binding domain (S1S2J) in complex with the compound ( S) - 1- [2'-Amino-2'-carboxyethyl]-6-methyl-5 ,7- dihydropyrrolo[3,4-d]pyrimidin-2,4(1H,3H)-dione at resolution 1.00A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Glutamate receptor 2,Glutamate receptor 2 | polymer | 264 | 29278.7 | 1 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) Pfam (PF00497) In PDB | Rattus norvegicus (Norway Rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
2 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
4 | A | LITHIUM ION | non-polymer | 6.9 | 1 | Chemie (LI) | |||
5 | A | (2~{S})-2-azanyl-3-[6-methyl-2,4-bis(oxidanylidene)-5,7-dihydropyrrolo[3,4-d]pyrimidin-1-yl]propanoic acid | non-polymer | 254.2 | 1 | Chemie (CG8) | |||
6 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
7 | water | water | 18.0 | 465 | Chemie (HOH) |
Sequence modifications
A: 3 - 117 (UniProt: P19491)
A: 120 - 264 (UniProt: P19491)
PDB | External Database | Details |
---|---|---|
Gly 1 | - | expression tag |
Ala 2 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 118 | - | linker |
Thr 119 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 29278.7 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1084.7 | |
All* | Total formula weight | 30363.5 |