6YIH
Structure of Chromosomal Passenger Complex (CPC) bound to phosphorylated Histone 3 peptide at 2.6 A.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Baculoviral IAP repeat-containing protein 5 | polymer | 144 | 16568.9 | 1 | UniProt (O15392) Pfam (PF00653) | Homo sapiens (Human) | Apoptosis inhibitor 4,Apoptosis inhibitor survivin |
| 2 | B (B) | Borealin | polymer | 67 | 8164.5 | 1 | UniProt (Q53HL2) Pfam (PF10444) | Homo sapiens (Human) | Cell division cycle-associated protein 8,Dasra-B,hDasra-B,Pluripotent embryonic stem cell-related gene 3 protein |
| 3 | C (C) | Inner centromere protein | polymer | 76 | 9224.6 | 1 | UniProt (Q9NQS7) Pfam (PF12178) | Homo sapiens (Human) | |
| 4 | D (D) | Histone H3.1 | polymer | 12 | 1388.5 | 1 | UniProt (P68431) | Homo sapiens | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 5 | E (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | F (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
A: 1 - 142 (UniProt: O15392)
C: 5 - 80 (UniProt: Q9NQS7)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 5 | Ala 5 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 35346.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 161.5 | |
| All* | Total formula weight | 35507.9 |
