6YHR
Crystal structure of Werner syndrome helicase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Werner syndrome ATP-dependent helicase | polymer | 585 | 66855.7 | 1 | UniProt (Q14191) Pfam (PF00270) Pfam (PF00271) Pfam (PF16124) Pfam (PF09382) In PDB | Homo sapiens (Human) | DNA helicase,RecQ-like type 3,RecQ3,Exonuclease WRN,RecQ protein-like 2 |
| 2 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 195 | Chemie (HOH) |
Sequence modifications
A: 517 - 1094 (UniProt: Q14191)
| PDB | External Database | Details |
|---|---|---|
| Met 516 | - | initiating methionine |
| Phe 1074 | Leu 1074 | variant |
| Ala 1094 | Val 1094 | expression tag |
| Glu 1095 | - | expression tag |
| Asn 1096 | - | expression tag |
| Leu 1097 | - | expression tag |
| Tyr 1098 | - | expression tag |
| Phe 1099 | - | expression tag |
| Gln 1100 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 66855.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 558.0 | |
| All* | Total formula weight | 67413.8 |
