6YBW
Structure of a human 48S translational initiation complex - 40S body
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | C | 40S ribosomal protein S4, X isoform | polymer | 263 | 29654.9 | 1 | UniProt (P62701) Pfam (PF08071) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) In PDB | Homo sapiens (Human) | SCR10,Single copy abundant mRNA protein,Small ribosomal subunit protein eS4, eS4 |
| 2 | B | 40S ribosomal protein S11 | polymer | 157 | 18321.7 | 1 | UniProt (P62280) Pfam (PF16205) Pfam (PF00366) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS17, uS17 |
| 3 | E | 40S ribosomal protein S23 | polymer | 143 | 15844.7 | 1 | UniProt (P62266) Pfam (PF00164) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS12, uS12 |
| 4 | D | 40S ribosomal protein S9 | polymer | 194 | 22641.6 | 1 | UniProt (P46781) Pfam (PF00163) Pfam (PF01479) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS4, uS4 |
| 5 | G | 40S ribosomal protein S7 | polymer | 194 | 22168.9 | 1 | UniProt (P62081) Pfam (PF01251) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS7, eS7 |
| 6 | F | 40S ribosomal protein S30 | polymer | 59 | 6668.9 | 1 | UniProt (P62861) Pfam (PF04758) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS30, eS30 |
| 7 | H | 40S ribosomal protein S27 | polymer | 84 | 9480.2 | 1 | UniProt (P42677) Pfam (PF01667) In PDB | Homo sapiens (Human) | Metallopan-stimulin 1,MPS-1,Small ribosomal subunit protein eS27, eS27 |
| 8 | K | 40S ribosomal protein S21 | polymer | 83 | 9124.4 | 1 | UniProt (P63220) Pfam (PF01249) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS21, eS21 |
| 9 | J | 40S ribosomal protein S15a | polymer | 130 | 14865.6 | 1 | UniProt (P62244) Pfam (PF00410) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS8, uS8 |
| 10 | M | 40S ribosomal protein S17 | polymer | 135 | 15578.2 | 1 | UniProt (P08708) Pfam (PF00833) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS17, eS17 |
| 11 | L | 40S ribosomal protein S2 | polymer | 293 | 31376.5 | 1 | UniProt (P15880) Pfam (PF00333) Pfam (PF03719) In PDB | Homo sapiens (Human) | 40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5, uS5 |
| 12 | O | 40S ribosomal protein S3a | polymer | 264 | 30002.1 | 1 | UniProt (P61247) Pfam (PF01015) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1 |
| 13 | N | 40S ribosomal protein SA | polymer | 295 | 32883.9 | 1 | UniProt (P08865) Pfam (PF00318) Pfam (PF16122) In PDB | Homo sapiens (Human) | 37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Colon carcinoma laminin-binding protein,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,Small ribosomal subunit protein uS2, uS2 |
| 14 | Q | 40S ribosomal protein S26 | polymer | 115 | 13047.5 | 1 | UniProt (P62854) Pfam (PF01283) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS26, eS26 |
| 15 | P | 40S ribosomal protein S14 | polymer | 151 | 16302.8 | 1 | UniProt (P62263) Pfam (PF00411) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS11, uS11 |
| 16 | S | 40S ribosomal protein S6 | polymer | 249 | 28751.9 | 1 | UniProt (P62753) Pfam (PF01092) In PDB | Homo sapiens (Human) | Phosphoprotein NP33,Small ribosomal subunit protein eS6, eS6 |
| 17 | R | 40S ribosomal protein S8 | polymer | 208 | 24263.4 | 1 | UniProt (P62241) Pfam (PF01201) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS8, eS8 |
| 18 | T | 40S ribosomal protein S24 | polymer | 133 | 15463.3 | 1 | UniProt (P62847) Pfam (PF01282) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein eS24, eS24 |
| 19 | q | Eukaryotic translation initiation factor 1A, X-chromosomal | polymer | 144 | 16488.4 | 1 | UniProt (P47813) Pfam (PF01176) In PDB | Homo sapiens (Human) | eIF-1A X isoform,Eukaryotic translation initiation factor 4C,eIF-4C |
| 20 | p | Eukaryotic translation initiation factor 1 | polymer | 113 | 12752.5 | 1 | UniProt (P41567) Pfam (PF01253) In PDB | Homo sapiens (Human) | eIF1,A121,Protein translation factor SUI1 homolog,Sui1iso1 |
| 21 | I | 40S ribosomal protein S13 | polymer | 151 | 17259.4 | 1 | UniProt (P62277) Pfam (PF08069) Pfam (PF00312) In PDB | Homo sapiens (Human) | Small ribosomal subunit protein uS15, uS15 |
| 22 | z | Eukaryotic translation initiation factor 3 subunit J | polymer | 258 | 29108.5 | 1 | UniProt (O75822) Pfam (PF08597) In PDB | Homo sapiens (Human) | eIF3j,Eukaryotic translation initiation factor 3 subunit 1,eIF-3-alpha,eIF3 p35 |
| 23 | y | Eukaryotic translation initiation factor 3 subunit C | polymer | 913 | 105503.9 | 1 | UniProt (Q99613) Pfam (PF05470) Pfam (PF01399) In PDB | Homo sapiens (Human) | eIF3c,Eukaryotic translation initiation factor 3 subunit 8,eIF3 p110 |
| 24 | 9 | 60S ribosomal protein L41 | polymer | 25 | 3473.5 | 1 | UniProt (P62945) Pfam (PF05162) In PDB | Homo sapiens (Human) | HG12,Large ribosomal subunit protein eL41, eL41 |
| 25 | A | 18S rRNA | polymer | 1869 | 603130.4 | 1 | Homo sapiens (Human) | ||
| 26 | 7 | mRNA | polymer | 28 | 9172.8 | 1 | Homo sapiens | ||
| 27 | L, A, S | MAGNESIUM ION | non-polymer | 24.3 | 60 | Chemie (MG) | |||
| 28 | Q | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 26 |
| Total formula weight | 1153329.7 | |
| Non-Polymers* | Number of molecules | 61 |
| Total formula weight | 1523.7 | |
| All* | Total formula weight | 1154853.4 |
