6YB9

Human octameric PAICS in complex with SAICAR, AMP-PNP, and magnesium

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Multifunctional protein ADE2	polymer	425	47135.1	2	UniProt (P22234) Pfam (PF01259) Pfam (PF00731)	Homo sapiens (Human)
2	C, L (A, B)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)
3	D, M (A, B)	(2~{S})-2-[[5-azanyl-1-[(2~{R},3~{R},4~{S},5~{R})-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]imidazol-4-yl]car bonylamino]butanedioic acid	non-polymer		454.3	2	Chemie (OK8)
4	E, F, G, H, K... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
5	I, J, O, P (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
6	Q, R (A, B)	water	water		18.0	286	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	94270.2
Non-Polymers*	Number of molecules	14
	Total formula weight	2390.6
All*	Total formula weight	96660.8

*Water molecules are not included.