6Y73
The crystal structure of human MACROD2 in space group P43
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | ADP-ribose glycohydrolase MACROD2 | polymer | 366 | 40906.8 | 8 | UniProt (A1Z1Q3) Pfam (PF01661) | Homo sapiens (Human) | MACRO domain-containing protein 2,O-acetyl-ADP-ribose deacetylase MACROD2,[Protein ADP-ribosylaspartate] hydrolase MACROD2,[Protein ADP-ribosylglutamate] hydrolase MACROD2 |
| 2 | I, J, M, O, P (A, B, C, D) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 3 | K, L, Q, S, T (B, C, F, G, H) | L(+)-TARTARIC ACID | non-polymer | 150.1 | 5 | Chemie (TLA) | |||
| 4 | N, R (C, F) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 5 | AA, BA, U, V, W... (G, H, A, B, C...) | water | water | 18.0 | 1593 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 7 - 243 (UniProt: A1Z1Q3)
| PDB | External Database | Details |
|---|---|---|
| Met -122 | - | initiating methionine |
| His -121 | - | expression tag |
| His -120 | - | expression tag |
| His -119 | - | expression tag |
| His -118 | - | expression tag |
| His -117 | - | expression tag |
| His -116 | - | expression tag |
| Ser -115 | - | expression tag |
| Ser -114 | - | expression tag |
| Gly -113 | - | expression tag |
| Met -112 | - | expression tag |
| Ser -111 | - | expression tag |
| Asp -110 | - | expression tag |
| Lys -109 | - | expression tag |
| Ile -108 | - | expression tag |
| Ile -107 | - | expression tag |
| His -106 | - | expression tag |
| Leu -105 | - | expression tag |
| Thr -104 | - | expression tag |
| Asp -103 | - | expression tag |
| Asp -102 | - | expression tag |
| Ser -101 | - | expression tag |
| Phe -100 | - | expression tag |
| Asp -99 | - | expression tag |
| Thr -98 | - | expression tag |
| Asp -97 | - | expression tag |
| Val -96 | - | expression tag |
| Leu -95 | - | expression tag |
| Lys -94 | - | expression tag |
| Ala -93 | - | expression tag |
| Asp -92 | - | expression tag |
| Gly -91 | - | expression tag |
| Ala -90 | - | expression tag |
| Ile -89 | - | expression tag |
| Leu -88 | - | expression tag |
| Val -87 | - | expression tag |
| Asp -86 | - | expression tag |
| Phe -85 | - | expression tag |
| Trp -84 | - | expression tag |
| Ala -83 | - | expression tag |
| Glu -82 | - | expression tag |
| Trp -81 | - | expression tag |
| Cys -80 | - | expression tag |
| Gly -79 | - | expression tag |
| Pro -78 | - | expression tag |
| Cys -77 | - | expression tag |
| Lys -76 | - | expression tag |
| Met -75 | - | expression tag |
| Ile -74 | - | expression tag |
| Ala -73 | - | expression tag |
| Pro -72 | - | expression tag |
| Ile -71 | - | expression tag |
| Leu -70 | - | expression tag |
| Asp -69 | - | expression tag |
| Glu -68 | - | expression tag |
| Ile -67 | - | expression tag |
| Ala -66 | - | expression tag |
| Asp -65 | - | expression tag |
| Glu -64 | - | expression tag |
| Tyr -63 | - | expression tag |
| Gln -62 | - | expression tag |
| Gly -61 | - | expression tag |
| Lys -60 | - | expression tag |
| Leu -59 | - | expression tag |
| Thr -58 | - | expression tag |
| Val -57 | - | expression tag |
| Ala -56 | - | expression tag |
| Lys -55 | - | expression tag |
| Leu -54 | - | expression tag |
| Asn -53 | - | expression tag |
| Ile -52 | - | expression tag |
| Asp -51 | - | expression tag |
| Gln -50 | - | expression tag |
| Asn -49 | - | expression tag |
| Pro -48 | - | expression tag |
| Gly -47 | - | expression tag |
| Thr -46 | - | expression tag |
| Ala -45 | - | expression tag |
| Pro -44 | - | expression tag |
| Lys -43 | - | expression tag |
| Tyr -42 | - | expression tag |
| Gly -41 | - | expression tag |
| Ile -40 | - | expression tag |
| Arg -39 | - | expression tag |
| Gly -38 | - | expression tag |
| Ile -37 | - | expression tag |
| Pro -36 | - | expression tag |
| Thr -35 | - | expression tag |
| Leu -34 | - | expression tag |
| Leu -33 | - | expression tag |
| Leu -32 | - | expression tag |
| Phe -31 | - | expression tag |
| Lys -30 | - | expression tag |
| Asn -29 | - | expression tag |
| Gly -28 | - | expression tag |
| Glu -27 | - | expression tag |
| Val -26 | - | expression tag |
| Ala -25 | - | expression tag |
| Ala -24 | - | expression tag |
| Thr -23 | - | expression tag |
| Lys -22 | - | expression tag |
| Val -21 | - | expression tag |
| Gly -20 | - | expression tag |
| Ala -19 | - | expression tag |
| Leu -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Lys -16 | - | expression tag |
| Gly -15 | - | expression tag |
| Gln -14 | - | expression tag |
| Leu -13 | - | expression tag |
| Lys -12 | - | expression tag |
| Glu -11 | - | expression tag |
| Phe -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Asp -8 | - | expression tag |
| Ala -7 | - | expression tag |
| Asn -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Ala -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Thr -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Asn 0 | - | expression tag |
| Leu 1 | - | expression tag |
| Tyr 2 | - | expression tag |
| Phe 3 | - | expression tag |
| Gln 4 | - | expression tag |
| Ser 5 | - | expression tag |
| Met 6 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 327254.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1367.2 | |
| All* | Total formula weight | 328621.9 |
